P35268 (RPL22)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: RL22_HUMAN

UniProtID: P35268

Gene name(s): RPL22

Protein name: 60S ribosomal protein L22

Gene ID: 6146

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P35268-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.628).
Combined Score: 0.998


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
306Ribosome, cytoplasmic800.10 (8/80)14681386CORUMView
30860S ribosomal subunit, cytoplasmic470.13 (6/47)14681386CORUMView
122660S ribosomal subunit, cytoplasmic30.33 (1/3)NAhu.MAPView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView

Human tissue specific expression (TPM)

Small intestine: 505.5 Liver: 255.0 Gallbladder: 345.9 Duodenum: 480.2 Rectum: 353.0 Tonsil: 463.4 Stomach: 391.8 Salivary glanda: 266.6 Adipose tissue: 536.3 Lung: 416.8 Lymph node: 765.3 Pancreas: 146.0 Kidney: 417.6 Colon: 449.0 Appendix: 681.4 Smooth musle: 368.4 Breast: 592.1 Parathyroid gland: 329.1 Esophagus: 415.9 Heart muscle: 200.9 Spleen: 688.2 Skeletal muscle: 317.6 Bone marrow: 648.3 Skin: 573.7 Urinary bladder: 366.2 Cervix, uterine: 422.0 Endometrium: 746.0 Ovary: 1343.4 Fallopian tube: 532.7 Seminal vesicle: 306.0 Prostate: 525.6 Epididymis: 382.6 Testis: 266.6 Placenta: 441.1 Thyroid gland: 504.2 Cerebral cortex: 378.4 Adrenal gland: 638.7
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000116251
Gene description:Ribosomal protein L22
Chromosome:1
Position6181269-6209389
Protein class:Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Nucleoli