P31943 (HNRNPH1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: HNRH1_HUMAN

UniProtID: P31943

Gene name(s): HNRNPH1;HNRPH;HNRPH1

Protein name: Heterogeneous nuclear ribonucleoprotein H

Gene ID: 3187

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P31943-P27958biogrid,HPIDB22810585affinity chromatography technology

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.972). Show
DDI evidence: yes (score 0.091). Show
Machine learning evidence: yes (score 0.229).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1181C complex spliceosome800.06 (5/80)11991638CORUMView
1287HNRPF-HNRPH1 complex20.50 (1/2)9858532CORUMView
1288DCS complex (PTBP1, PTBP2, HNRPH1, HNRPF)40.25 (1/4)11003644CORUMView
1332Large Drosha complex200.15 (3/20)15531877CORUMView
3082DGCR8 multiprotein complex110.36 (4/11)17765891CORUMView
7381DCS complex40.25 (1/4)11003644CORUMView
151Large Drosha complex20.50 (1/2)NAhu.MAPView
818C complex spliceosome90.33 (3/9)NAhu.MAPView
984Large Drosha complex30.33 (1/3)NAhu.MAPView
1737Large Drosha complex20.50 (1/2)NAhu.MAPView
2394C complex spliceosome110.36 (4/11)NAhu.MAPView
2705HNRPF-HNRPH1 complex50.60 (3/5)NAhu.MAPView
3267HNRPF-HNRPH1 complex30.33 (1/3)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE46041iPS-derived_neurons_uninfectediPS-derived_neurons_HSV-1-infectedup1.754.42e-04Microarray data
GSE50938polysomal_RNA_mock-infected_NHDFspolysomal_RNA_HCMV-infected_HNDFs_48h_post-infectionup1.722.25e-03Microarray data

Human tissue specific expression (TPM)

Small intestine: 104.1 Liver: 45.6 Gallbladder: 108.8 Duodenum: 80.7 Rectum: 97.8 Tonsil: 155.5 Stomach: 74.1 Salivary glanda: 41.7 Adipose tissue: 123.7 Lung: 128.0 Lymph node: 200.9 Pancreas: 19.3 Kidney: 86.0 Colon: 101.5 Appendix: 143.3 Smooth musle: 152.4 Breast: 77.4 Parathyroid gland: 97.3 Esophagus: 88.5 Heart muscle: 48.4 Spleen: 188.7 Skeletal muscle: 53.1 Bone marrow: 175.2 Skin: 140.2 Urinary bladder: 89.0 Cervix, uterine: 100.3 Endometrium: 203.6 Ovary: 184.0 Fallopian tube: 155.3 Seminal vesicle: 72.4 Prostate: 111.4 Epididymis: 96.8 Testis: 169.4 Placenta: 111.0 Thyroid gland: 132.9 Cerebral cortex: 124.7 Adrenal gland: 119.9
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000169045
Gene description:Heterogeneous nuclear ribonucleoprotein H1
Chromosome:5
Position179614178-179634784
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm, Cytosol