P31942 (HNRNPH3)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: HNRH3_HUMAN

UniProtID: P31942

Gene name(s): HNRNPH3;HNRPH3

Protein name: Heterogeneous nuclear ribonucleoprotein H3

Gene ID: 3189

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P31942-P27958biogrid,HPIDB22810585affinity chromatography technology

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.972). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.162).
Combined Score: 0.968


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3HNRNPH3-HNRNPA1L221.00 (2/2)NAhu.MAPView
1078HMBS-VPS4A-HNRNPH3-HNRNPA1L240.50 (2/4)NAhu.MAPView
1801Large Drosha complex70.14 (1/7)NAhu.MAPView
1903HMBS-KRIT1-ECI1-HNRNPH340.25 (1/4)NAhu.MAPView
2264Large Drosha complex60.17 (1/6)NAhu.MAPView
2353PIN1-AUF1 complex40.25 (1/4)NAhu.MAPView
2364HNRNPAB-EIF4H-HNRNPA1-HNRNPL-HNRNPDL-HNRNPH360.33 (2/6)NAhu.MAPView
3335C complex spliceosome80.50 (4/8)NAhu.MAPView
3345HNRNPDL-HNRNPH3-HNRNPAB30.33 (1/3)NAhu.MAPView
3834Large Drosha complex60.17 (1/6)NAhu.MAPView
3930Large Drosha complex60.17 (1/6)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_24hVN1203_infected_24hup2.433.49e-04Microarray data
GSE59226ControlVirus_infectionup1.961.29e-04Microarray data
GSE65574MCL001_mock_0hMCL001_RFP-MERS_0hdown-2.357.17e-03Microarray data
GSE65574MCL001_mock_12hMCL001_d4B-MERS_12hdown-1.836.24e-05Microarray data
GSE65574MCL001_mock_12hMCL001_RFP-MERS_12hdown-1.671.32e-02Microarray data
GSE65574MCL001_mock_7hMCL001_RFP-MERS_7hdown-2.022.83e-03Microarray data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hup1.813.18e-10RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hup2.783.90e-30RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hup2.172.97e-14RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_12hMDM-513_H5N1_MOI2_12hup2.401.71e-19RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 72.1 Liver: 29.3 Gallbladder: 70.7 Duodenum: 55.5 Rectum: 70.9 Tonsil: 71.3 Stomach: 51.5 Salivary glanda: 20.2 Adipose tissue: 73.6 Lung: 78.2 Lymph node: 91.2 Pancreas: 7.6 Kidney: 71.0 Colon: 64.6 Appendix: 88.6 Smooth musle: 101.3 Breast: 69.0 Parathyroid gland: 102.5 Esophagus: 49.2 Heart muscle: 44.2 Spleen: 85.0 Skeletal muscle: 31.6 Bone marrow: 61.6 Skin: 75.6 Urinary bladder: 58.7 Cervix, uterine: 98.5 Endometrium: 154.2 Ovary: 136.0 Fallopian tube: 108.5 Seminal vesicle: 84.2 Prostate: 97.5 Epididymis: 55.0 Testis: 128.4 Placenta: 119.7 Thyroid gland: 126.5 Cerebral cortex: 93.9 Adrenal gland: 86.2
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000096746
Gene description:Heterogeneous nuclear ribonucleoprotein H3
Chromosome:10
Position68331174-68343191
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm