Human protein: TYY1_HUMAN
UniProtID: P25490
Gene name(s): YY1;INO80S
Protein name: Transcriptional repressor protein YY1
Gene ID: 7528
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P25490-P27958 | biogrid,HPIDB | 16170350 | pull down |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.171). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 116 | Polycomb repressive complex 1 (PRC1, hPRC-H) | 13 | 0.15 (2/13) | 12167701 | CORUM | View |
| 2918 | Ku antigen-YY1-alphaMyHC promoter complex | 3 | 0.33 (1/3) | 15367688 | CORUM | View |
| 2946 | YY1-Notch1-RBP-Jkappa complex | 3 | 0.33 (1/3) | 12913000 | CORUM | View |
| 2947 | YY1-Notch1 complex | 2 | 0.50 (1/2) | 12913000 | CORUM | View |
| 3045 | hs4 enhancer complex (faster migrating complex) | 5 | 0.20 (1/5) | 14707079 | CORUM | View |
| 3046 | hs4 enhancer complex (slow migrating complex) | 2 | 0.50 (1/2) | 14707079 | CORUM | View |
| 5331 | YY1-MDM2-p53 complex | 3 | 0.67 (2/3) | 15210108 | CORUM | View |
| 5502 | EED-EZH-YY1 polycomb complex | 3 | 0.33 (1/3) | 11158321 | CORUM | View |
| 1888 | INO80 chromatin remodeling complex | 12 | 0.08 (1/12) | NA | hu.MAP | View |
| 2103 | INO80 chromatin remodeling complex | 6 | 0.17 (1/6) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE28166 | mock_infected_24h | VN1203_infected_24h | up | 1.58 | 2.17e-04 | Microarray data |
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_WT_15hpi | down | -1.50 | 9.20e-06 | Microarray data |
| GSE32140-GPL6480 | mock_for_RSV_2h | RSV_infection | down | -2.25 | 1.93e-05 | Microarray data |
| GSE65574 | MCL001_mock_0h | MCL001_d3-5-MERS_0h | up | 1.59 | 3.08e-02 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d3-5-MERS_12h | up | 2.21 | 5.44e-04 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000100811 |
| Gene description: | YY1 transcription factor |
| Chromosome: | 14 |
| Position | 100238298-100282792 |
| Protein class: | Plasma proteins, Predicted intracellular proteins, Transcription factors |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Nucleoli fibrillar center, Vesicles |