P24666 (ACP1)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: PPAC_HUMAN

UniProtID: P24666

Gene name(s): ACP1

Protein name: Low molecular weight phosphotyrosine protein phosphatase

Gene ID: 52

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P24666-P27958-PRO_0000037566HPIDB15846844pull down

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.631). Show
DDI evidence: yes (score 0.006). Show
Machine learning evidence: yes (score 0.776).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
2294UBE2M-ACP120.50 (1/2)NAhu.MAPView
3540CSRP1-CELF1-ACP130.33 (1/3)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-1.532.98e-06Microarray data
GSE65123healthy_seronegative_controlHCV_infecteddown-2.924.21e-02Microarray data

Human tissue specific expression (TPM)

Small intestine: 65.6 Liver: 54.2 Gallbladder: 70.1 Duodenum: 62.0 Rectum: 69.6 Tonsil: 55.0 Stomach: 59.3 Salivary glanda: 30.0 Adipose tissue: 41.5 Lung: 69.9 Lymph node: 73.9 Pancreas: 19.3 Kidney: 82.2 Colon: 59.0 Appendix: 59.0 Smooth musle: 60.7 Breast: 78.4 Parathyroid gland: 84.5 Esophagus: 46.4 Heart muscle: 37.0 Spleen: 60.5 Skeletal muscle: 26.4 Bone marrow: 55.6 Skin: 47.3 Urinary bladder: 52.8 Cervix, uterine: 65.4 Endometrium: 76.7 Ovary: 70.6 Fallopian tube: 91.1 Seminal vesicle: 60.5 Prostate: 82.3 Epididymis: 81.8 Testis: 85.6 Placenta: 88.1 Thyroid gland: 105.1 Cerebral cortex: 83.8 Adrenal gland: 128.8
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000143727
Gene description:Acid phosphatase 1, soluble
Chromosome:2
Position264140-278283
Protein class:Enzymes, Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Cytosol