Human protein: ROA2_HUMAN
UniProtID: P22626
Gene name(s): HNRNPA2B1;HNRPA2B1
Protein name: Heterogeneous nuclear ribonucleoproteins A2/B1
Gene ID: 3181
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P22626-P27958 | biogrid,HPIDB | 22810585 | affinity chromatography technology |
| Interolog evidence: | yes (score 0.994). | Show |
| DDI evidence: | none/insignificant. | |
| Machine learning evidence: | yes (score 0.160). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 1181 | C complex spliceosome | 80 | 0.06 (5/80) | 11991638 | CORUM | View |
| 999 | p23 protein complex | 3 | 0.33 (1/3) | 14675759 | CORUM | View |
| 818 | C complex spliceosome | 9 | 0.33 (3/9) | NA | hu.MAP | View |
| 1005 | C complex spliceosome | 8 | 0.12 (1/8) | NA | hu.MAP | View |
| 2394 | C complex spliceosome | 11 | 0.36 (4/11) | NA | hu.MAP | View |
| 3335 | C complex spliceosome | 8 | 0.50 (4/8) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE59226 | Control | Virus_infection | down | -1.84 | 3.47e-04 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_WT_infected_96h | down | -1.62 | 3.73e-02 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000122566 |
| Gene description: | Heterogeneous nuclear ribonucleoprotein A2/B1 |
| Chromosome: | 7 |
| Position | 26189927-26201529 |
| Protein class: | Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm |