Human protein: RL7_HUMAN
UniProtID: P18124
Gene name(s): RPL7
Protein name: 60S ribosomal protein L7
Gene ID: 6129
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P18124-P27958 | PHISTO | 17229681 | anti tag coimmunoprecipitation |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.003). | Show |
| Machine learning evidence: | yes (score 0.179). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 3055 | Nop56p-associated pre-rRNA complex | 104 | 0.12 (12/104) | 12777385 | CORUM | View |
| 306 | Ribosome, cytoplasmic | 80 | 0.10 (8/80) | 14681386 | CORUM | View |
| 308 | 60S ribosomal subunit, cytoplasmic | 47 | 0.13 (6/47) | 14681386 | CORUM | View |
| 5380 | TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) | 25 | 0.12 (3/25) | 17507929 | CORUM | View |
| 2146 | Ribosome, cytoplasmic | 143 | 0.13 (18/143) | NA | hu.MAP | View |
| 2985 | Ribosome, cytoplasmic | 139 | 0.12 (16/139) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE32155 | CRL-5810_unifected | CRL-5807_infected | up | 1.53 | 2.10e-04 | Microarray data |
| GSE65574 | MCL001_mock_0h | MCL001_RFP-MERS_0h | down | -1.72 | 9.53e-03 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | down | -2.68 | 9.31e-05 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_RFP-MERS_12h | down | -1.98 | 8.48e-03 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_WT_infected_96h | down | -2.90 | 4.11e-02 | RNA-Seq data |
| GSE65574 | MCL001_mock_7h | MCL001_RFP-MERS_7h | down | -2.12 | 7.43e-04 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_NS1_L132A_L133A_infected_96h | down | -3.80 | 5.35e-05 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000147604 |
| Gene description: | Ribosomal protein L7 |
| Chromosome: | 8 |
| Position | 73290267-73295789 |
| Protein class: | Plasma proteins, Predicted intracellular proteins, Ribosomal proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoli, Endoplasmic reticulum, Cytosol |