Human protein: HXD8_HUMAN
UniProtID: P13378
Gene name(s): HOXD8;HOX4E
Protein name: Homeobox protein Hox-D8
Gene ID: 3234
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P13378-P27958 | biogrid,HPIDB | 18985028 | two hybrid |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.261). |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE13637 | HUVEC_control | PR8-infected_IKK2kd-transfected_HUVEC | up | 1.68 | 2.78e-05 | Microarray data |
| GSE13637 | HUVEC_control | PR8-infected_pEGZ-transfected_HUVEC | up | 1.68 | 1.23e-05 | Microarray data |
| GSE32155 | CRL-5800_unifected | CRL-1472_infected | down | -5.07 | 2.34e-06 | Microarray data |
| GSE32155 | CRL-5800_unifected | CRL-5807_infected | down | -5.23 | 9.52e-07 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | down | -6.36 | 6.76e-06 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-5807_infected | down | -6.52 | 3.86e-06 | Microarray data |
| GSE32155 | HTB-3_unifected | HTB-174_infected | down | -5.40 | 6.86e-07 | Microarray data |
| GSE32155 | HTB-4_unifected | HTB-174_infected | down | -7.07 | 5.65e-07 | Microarray data |
| GSE85493 | MeWo_uninfected_24h | MeWo_Y881-920F_infected_24h | down | -1.58 | 4.98e-02 | RNA-Seq data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | up | 2.04 | 4.00e-05 | Microarray data |
| GSE99389 | CD4+_mock_infected_1d | EBOV_infected_1d | up | 4.87 | 2.61e-02 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_12h | MDM-520_H5N1_MOI2_12h | up | 6.72 | 2.97e-02 | RNA-Seq data |
| GSE97672-GPL18573 | MDM-513_H5N1_MOI0_12h | MDM-513_H5N1_MOI2_12h | up | 7.05 | 6.44e-03 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Tissue enhanced:
| Tissue | Expression (TPM) |
|---|---|
| epididymis | 122.0 |
| kidney | 83.6 |
| Ensembl ID: | ENSG00000175879 |
| Gene description: | Homeobox D8 |
| Chromosome: | 2 |
| Position | 176129694-176132695 |
| Protein class: | Predicted intracellular proteins, Transcription factors |
| Evidence: | Evidence at transcript level |
| Subcellular location: |