P12236 (SLC25A6)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: ADT3_HUMAN

UniProtID: P12236

Gene name(s): SLC25A6;ANT3;CDABP0051

Protein name: ADP/ATP translocase 3

Gene ID: 293

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P12236-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.907). Show
DDI evidence: yes (score 0.003). Show
Machine learning evidence: yes (score 0.235).
Combined Score: 0.988


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
128F1F0-ATP synthase, mitochondrial70.29 (2/7)NAhu.MAPView
850SLC25A20-SLC25A620.50 (1/2)NAhu.MAPView
990Nop56p-associated pre-rRNA complex80.25 (2/8)NAhu.MAPView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE102481mock_infected_18hRVFV_ZH548_infected_18hup1.651.04e-02RNA-Seq data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-1.611.67e-05Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-1.844.53e-06Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-1.669.41e-06Microarray data
GSE50938polysomal_RNA_mock-infected_NHDFspolysomal_RNA_HCMV-infected_HNDFs_48h_post-infectionup1.833.57e-02Microarray data
GSE59226ControlVirus_infectiondown-2.251.56e-04Microarray data

Human tissue specific expression (TPM)

Small intestine: 261.5 Liver: 25.6 Gallbladder: 118.7 Duodenum: 286.7 Rectum: 99.3 Tonsil: 94.4 Stomach: 158.7 Salivary glanda: 195.2 Adipose tissue: 215.6 Lung: 128.1 Lymph node: 185.8 Pancreas: 79.5 Kidney: 160.3 Colon: 166.4 Appendix: 178.6 Smooth musle: 119.6 Breast: 142.4 Parathyroid gland: 159.8 Esophagus: 116.3 Heart muscle: 66.5 Spleen: 226.4 Skeletal muscle: 26.5 Bone marrow: 170.7 Skin: 137.8 Urinary bladder: 106.6 Cervix, uterine: 130.6 Endometrium: 188.2 Ovary: 291.7 Fallopian tube: 167.7 Seminal vesicle: 165.0 Prostate: 176.6 Epididymis: 64.2 Testis: 63.2 Placenta: 132.5 Thyroid gland: 189.6 Cerebral cortex: 150.7 Adrenal gland: 238.7
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000169100
Gene description:Solute carrier family 25 member 6
Chromosome:X
Position1386152-1392724
Protein class:FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters
Evidence:Evidence at protein level
Subcellular location:Mitochondria