Human protein: CH60_HUMAN
UniProtID: P10809
Gene name(s): HSPD1;HSP60
Protein name: 60 kDa heat shock protein
Gene ID: 3329
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P10809-P27958 | PHISTO,biogrid,HPIDB,VirusMentha | 22810585 | affinity chromatography technology,tandem affinity purification |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 1094 | Frataxin complex | 7 | 0.14 (1/7) | 17331979 | CORUM | View |
| 2755 | 17S U2 snRNP | 33 | 0.09 (3/33) | 12234937 | CORUM | View |
| 611 | RCN1-BTF3-NACA2-HSPD1-CALU-DLST | 6 | 0.33 (2/6) | NA | hu.MAP | View |
| 1083 | HSPD1-LRRC28 | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 3412 | DBC1-SIRT1 complex | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 4519 | HSPD1-ATP5A1-NACA2-BTF3-CALU-DLST | 6 | 0.33 (2/6) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE102481 | mock_infected_18h | RVFV_ZH548_infected_18h | down | -1.80 | 4.87e-11 | RNA-Seq data |
| GSE32155 | CRL-5800_unifected | CRL-1472_infected | down | -1.59 | 5.59e-05 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | down | -1.89 | 1.72e-04 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_NL219_pCalu3_24h | down | -1.92 | 1.69e-06 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000144381 |
| Gene description: | Heat shock protein family D (Hsp60) member 1 |
| Chromosome: | 2 |
| Position | 197486581-197516737 |
| Protein class: | Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Mitochondria |