P09651 (HNRNPA1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: ROA1_HUMAN

UniProtID: P09651

Gene name(s): HNRNPA1;HNRPA1

Protein name: Heterogeneous nuclear ribonucleoprotein A1

Gene ID: 3178

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P09651-P27958PHISTO,biogrid,HPIDB17229681,22810585affinity chromatography technology,anti bait coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.978). Show
DDI evidence: yes (score 0.097). Show
Machine learning evidence: yes (score 0.171).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1181C complex spliceosome800.06 (5/80)11991638CORUMView
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
818C complex spliceosome90.33 (3/9)NAhu.MAPView
1938SAFB2-HNRNPA3-ZNF326-KHDRBS1-SAFB-HNRNPA0-HNRNPA1-RBM3-SLTM-ADAR-ILF3110.09 (1/11)NAhu.MAPView
2364HNRNPAB-EIF4H-HNRNPA1-HNRNPL-HNRNPDL-HNRNPH360.33 (2/6)NAhu.MAPView
2394C complex spliceosome110.36 (4/11)NAhu.MAPView
3193HNRNPA0-HNRNPA1-RBM3-DUSP1140.25 (1/4)NAhu.MAPView
3335C complex spliceosome80.50 (4/8)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE65574MCL001_mock_24hMCL001_dNSP16-MERS_24hup1.607.73e-03Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hup1.563.04e-02Microarray data

Human tissue specific expression (TPM)

Small intestine: 515.2 Liver: 153.0 Gallbladder: 439.6 Duodenum: 486.7 Rectum: 563.2 Tonsil: 758.3 Stomach: 418.9 Salivary glanda: 178.1 Adipose tissue: 471.8 Lung: 518.6 Lymph node: 890.2 Pancreas: 85.9 Kidney: 413.3 Colon: 532.4 Appendix: 798.1 Smooth musle: 683.5 Breast: 741.8 Parathyroid gland: 711.4 Esophagus: 382.5 Heart muscle: 233.5 Spleen: 676.0 Skeletal muscle: 105.3 Bone marrow: 977.2 Skin: 548.8 Urinary bladder: 459.9 Cervix, uterine: 686.9 Endometrium: 1180.1 Ovary: 1919.7 Fallopian tube: 829.4 Seminal vesicle: 559.8 Prostate: 610.6 Epididymis: 649.8 Testis: 354.4 Placenta: 729.2 Thyroid gland: 564.1 Cerebral cortex: 513.5 Adrenal gland: 570.1
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000135486
Gene description:Heterogeneous nuclear ribonucleoprotein A1
Chromosome:12
Position54280193-54287088
Protein class:Disease related genes, Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm