Human protein: SRP19_HUMAN
UniProtID: P09132
Gene name(s): SRP19
Protein name: Signal recognition particle 19 kDa protein
Gene ID: 6728
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P09132-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.017). | Show |
| Machine learning evidence: | yes (score 0.095). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2334 | SRP54-SRP19-RWDD1 | 3 | 0.33 (1/3) | NA | hu.MAP | View |
| 4277 | TFB1M-PRRC2C-CKAP2-HIST1H3A-SRP72-RNMTL1-SPATS2L-SRP19 | 8 | 0.12 (1/8) | NA | hu.MAP | View |
| 4475 | BLM-TOP3A complex | 8 | 0.12 (1/8) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE19345 | Mock_infected | HCMV_infected_12h | up | 1.52 | 3.81e-04 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_Anhui01_pCalu3_24h | up | 1.62 | 2.08e-07 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_NL219_pCalu3_24h | up | 2.44 | 2.77e-07 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_Pan99_pCalu3_24h | up | 1.77 | 7.58e-07 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_VN1203_pCalu3_24h | up | 2.10 | 1.23e-07 | Microarray data |
| GSE65123 | healthy_seronegative_control | HCV_infected | down | -3.17 | 4.04e-02 | Microarray data |
| GSE71766 | BEAS-2B_control_baseline | BEAS-2B_RhinoVirus_72hrs | up | 1.53 | 8.49e-14 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000153037 |
| Gene description: | Signal recognition particle 19 |
| Chromosome: | 5 |
| Position | 112861222-112869788 |
| Protein class: | Predicted intracellular proteins, Transporters |
| Evidence: | Evidence at protein level |
| Subcellular location: |