Human protein: ANXA2_HUMAN
UniProtID: P07355
Gene name(s): ANXA2;ANX2;ANX2L4;CAL1H;LPC2D
Protein name: Annexin A2
Gene ID: 302
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P07355-P27958 | PHISTO | 22301157 | anti bait coimmunoprecipitation |
| Interolog evidence: | yes (score 0.631). | Show |
| DDI evidence: | none/insignificant. | |
| Machine learning evidence: | yes (score 0.222). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 7248 | ABCB1-ANXA2-RACK1-SRC complex | 4 | 0.50 (2/4) | 27754360 | CORUM | View |
| 780 | CART complex | 48 | 0.12 (6/48) | NA | hu.MAP | View |
| 1186 | ANXA2-S100A10 | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 1597 | TMTC3-ANXA2-S100A10 | 3 | 0.33 (1/3) | NA | hu.MAP | View |
| 1807 | ANXA13-ANXA2-S100A10 | 3 | 0.33 (1/3) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_DeltaE_15hpi | down | -2.22 | 4.44e-07 | Microarray data |
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_WT_15hpi | down | -2.12 | 4.99e-06 | Microarray data |
| GSE32155 | CRL-5800_unifected | CRL-5807_infected | up | 1.59 | 8.01e-04 | Microarray data |
| GSE43794 | NPCs_jCV_infection_0h | NPCs_jCV_infection_30d | up | 2.20 | 1.35e-08 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | down | -2.62 | 1.51e-03 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_RFP-MERS_12h | down | -1.76 | 1.19e-02 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_WT_infected_96h | up | 6.91 | 1.03e-04 | RNA-Seq data |
| GSE65574 | MCL001_mock_24h | MCL001_d4B-MERS_24h | down | -2.27 | 7.16e-03 | Microarray data |
| GSE99389 | CD4+_mock_infected_4d | LPS_infected_4d | down | -1.70 | 4.44e-07 | RNA-Seq data |
| GSE99298 | mock_infected_0h | hRSV_NS1_L132A_L133A_infected_96h | up | 6.51 | 6.23e-03 | RNA-Seq data |
| GSE99298 | mock_infected_0h | hRSV_NS1_Y125A_infected_96h | up | 6.07 | 4.18e-07 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_18h | MDM-520_H5N1_MOI2_18h | down | -1.57 | 7.39e-17 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000182718 |
| Gene description: | Annexin A2 |
| Chromosome: | 15 |
| Position | 60347134-60402883 |
| Protein class: | Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters |
| Evidence: | Evidence at protein level |
| Subcellular location: |