P05455 (SSB)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: LA_HUMAN

UniProtID: P05455

Gene name(s): SSB

Protein name: Lupus La protein

Gene ID: 6741

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P05455-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.005). Show
Machine learning evidence: yes (score 0.267).
Combined Score: 0.981


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1223H2AX complex, isolated from cells without IR exposure130.38 (5/13)16522924CORUMView
5613Emerin complex 25160.12 (2/16)17620012CORUMView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE84188mock_infected_2dEBOV_infected_2dup1.739.75e-09RNA-Seq data
GSE24238Mock_24hHCMV_24hup2.311.67e-02Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-3.361.80e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-3.613.68e-07Microarray data
GSE97672-GPL16791MDM-315_H1N1_MOI0_06hMDM-315_H1N1_MOI2_06hup1.702.31e-28RNA-Seq data
GSE97672-GPL16791MDM-315_H1N1_MOI0_12hMDM-315_H1N1_MOI2_12hup1.703.64e-18RNA-Seq data
GSE97672-GPL16791MDM-315_H1N1_MOI0_18hMDM-315_H1N1_MOI2_18hup1.582.90e-11RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 52.5 Liver: 33.4 Gallbladder: 88.4 Duodenum: 47.4 Rectum: 60.8 Tonsil: 71.1 Stomach: 44.5 Salivary glanda: 20.8 Adipose tissue: 120.3 Lung: 80.0 Lymph node: 103.2 Pancreas: 7.3 Kidney: 76.3 Colon: 51.1 Appendix: 98.6 Smooth musle: 86.3 Breast: 82.3 Parathyroid gland: 120.4 Esophagus: 54.2 Heart muscle: 43.3 Spleen: 83.1 Skeletal muscle: 16.8 Bone marrow: 62.9 Skin: 53.0 Urinary bladder: 78.1 Cervix, uterine: 85.3 Endometrium: 110.0 Ovary: 81.6 Fallopian tube: 94.5 Seminal vesicle: 78.7 Prostate: 120.9 Epididymis: 95.8 Testis: 74.0 Placenta: 101.3 Thyroid gland: 131.2 Cerebral cortex: 99.5 Adrenal gland: 95.1
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000138385
Gene description:Sjogren syndrome antigen B
Chromosome:2
Position169791933-169812064
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm