Human protein: HLAA_HUMAN
UniProtID: P04439
Gene name(s): HLA-A;HLAA
Protein name: HLA class I histocompatibility antigen
Gene ID: 3105
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P04439-P27958 | PDB | 1610791 | NA |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.494). |
Color:
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2370 | HLA-A-HLA-C | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 3948 | HLA-G-HLA-A-HLA-C-HLA-F | 4 | 0.25 (1/4) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE84346 | uninfected_control | HCV_infected_high_ISG | up | 1.68 | 1.58e-02 | RNA-Seq data |
| GSE32140-GPL6480 | mock_for_influenza_2h | influenza_infection | up | 2.01 | 1.23e-05 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | up | 2.67 | 2.84e-04 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-5807_infected | up | 2.95 | 2.47e-04 | Microarray data |
| GSE47865 | mock_infected | SV_infected | up | 2.06 | 4.82e-07 | Microarray data |
| GSE93385 | K048_mock_infected | K048_ZIKV_infected | up | 2.28 | 1.95e-27 | RNA-Seq data |
| GSE59226 | Control | Virus_infection | down | -1.93 | 1.58e-04 | Microarray data |
| GSE64605 | HS_unifected | HS_R70_or_L91_infected | up | 1.65 | 7.90e-06 | Microarray data |
| GSE67198 | uninfected_control | 150HA_u_per_mL_Sev_infected | up | 1.81 | 1.34e-06 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_NS1_Y125A_infected_96h | up | 2.57 | 2.60e-02 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_18h | MDM-520_H5N1_MOI2_18h | down | -2.09 | 2.61e-22 | RNA-Seq data |
| GSE97672-GPL18573 | MDM-513_H5N1_MOI0_18h | MDM-513_H5N1_MOI2_18h | down | -2.53 | 6.71e-54 | RNA-Seq data |
| GSE8961 | Mock_infection | HMPV_infection_72h | up | 2.03 | 1.94e-05 | Microarray data |