P04114 (APOB)

Homo sapiens

P27958-PRO_0000037576 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: APOB_HUMAN

UniProtID: P04114

Gene name(s): APOB

Protein name: Apolipoprotein B-100

Gene ID: 338

HDF/HRF: NA

Virus protein: Non-structural protein 5A(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037576

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P04114-P27958-PRO_0000037576HPIDB16203724anti bait coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.089). Show
Machine learning evidence: yes (score 0.703).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
11SLC9A3R1-ACTN4 complex20.50 (1/2)NAhu.MAPView
1572BAIAP2L1-NUBP1-PSMD14-C19orf60-APOB50.20 (1/5)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE69602cytosol_unifectedcytosol_DENV2_infected_24hup2.864.47e-02RNA-Seq data
GSE69602ER_unifectedER_DENV2_infected_40hdown-1.654.68e-02RNA-Seq data
GSE38941nomal_liverHBV-associated_acute_liver_failure_liverdown-2.631.17e-04Microarray data
GSE89008HTBE_H1N1_MOI0_mock_infected_18hHTBE_H1N1_MOI5_infected_18hup26.432.14e-06RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 333.2 Liver: 618.9 Gallbladder: 0.8 Duodenum: 182.8 Rectum: 0.1 Tonsil: 0.0 Stomach: 0.3 Salivary glanda: 0.0 Adipose tissue: 3.1 Lung: 0.0 Lymph node: 0.3 Pancreas: 0.0 Kidney: 0.3 Colon: 0.0 Appendix: 0.3 Smooth musle: 0.3 Breast: 0.2 Parathyroid gland: 0.0 Esophagus: 0.1 Heart muscle: 1.9 Spleen: 0.2 Skeletal muscle: 0.0 Bone marrow: 0.0 Skin: 0.0 Urinary bladder: 0.1 Cervix, uterine: 1.1 Endometrium: 0.3 Ovary: 0.1 Fallopian tube: 0.0 Seminal vesicle: 0.1 Prostate: 0.3 Epididymis: 0.0 Testis: 0.5 Placenta: 0.0 Thyroid gland: 0.0 Cerebral cortex: 0.0 Adrenal gland: 0.0
Expression value is measured by Transcripts Per Million (TPM)
Group enriched:
TissueExpression (TPM)
duodenum 182.8
liver 618.9
small intestine 333.2
Ensembl ID:ENSG00000084674
Gene description:Apolipoprotein B
Chromosome:2
Position21001429-21044073
Protein class:Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins
Evidence:Evidence at protein level
Subcellular location:Vesicles, Cytosol