Human protein: FRIH_HUMAN
UniProtID: P02794
Gene name(s): FTH1;FTH;FTHL6;OK/SW-cl.84;PIG15
Protein name: Ferritin heavy chain
Gene ID: 2495
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P02794-P27958 | PHISTO,biogrid,HPIDB | 15607035,18985028 | two hybrid |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.111). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 6135 | Ferritin complex | 2 | 0.50 (1/2) | 8695634 | CORUM | View |
| 2633 | Ferritin complex | 2 | 0.50 (1/2) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE102481 | mock_infected_18h | RVFV_MP12_infected_18h | down | -1.96 | 3.68e-20 | RNA-Seq data |
| GSE102481 | mock_infected_18h | RVFV_ZH548_infected_18h | down | -1.69 | 2.31e-09 | RNA-Seq data |
| GSE79968 | IMR90_GFP_40h | IMR90_MCPyV_ST_40h | down | -1.88 | 2.72e-03 | RNA-Seq data |
| GSE79968 | IMR90_GFP_56h | IMR90_MCPyV_ST_56h | down | -1.60 | 4.78e-02 | RNA-Seq data |
| GSE79968 | IMR90_GFP_96h | IMR90_MCPyV_ST_96h | down | -1.75 | 1.49e-02 | RNA-Seq data |
| GSE45042 | ELC001_mock_infected_24h | ECL001_EMC_infected_24h | down | -1.89 | 7.20e-05 | Microarray data |
| GSE49628 | Bcells_Quiescent | Bcells_Activation | down | -2.04 | 1.98e-04 | Microarray data |
| GSE92496 | control_vector | HPV16_E6-E7_vector | down | -1.58 | 2.05e-03 | RNA-Seq data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | down | -3.00 | 3.38e-05 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_RFP-MERS_12h | down | -1.92 | 3.41e-03 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d3-5-MERS_24h | down | -2.24 | 2.72e-04 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_WT_infected_96h | down | -5.77 | 7.31e-04 | RNA-Seq data |
| GSE65574 | MCL001_mock_24h | MCL001_d4B-MERS_24h | down | -2.31 | 2.83e-04 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_dNSP16-MERS_24h | down | -1.68 | 5.49e-03 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_icMERS_24h | down | -2.05 | 1.47e-02 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_RFP-MERS_24h | down | -2.82 | 6.10e-03 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_NS1_L132A_L133A_infected_96h | down | -15.28 | 1.80e-20 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000167996 |
| Gene description: | Ferritin heavy chain 1 |
| Chromosome: | 11 |
| Position | 61959718-61967660 |
| Protein class: | Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Microtubules |