Human protein: APOC3_HUMAN
UniProtID: P02656
Gene name(s): APOC3
Protein name: Apolipoprotein C-III
Gene ID: 345
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P02656-P27958 | biogrid,HPIDB | 26845356 | two hybrid |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.047). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 403 | CP-LF complex | 9 | 0.22 (2/9) | NA | hu.MAP | View |
| 517 | CP-MPO complex | 8 | 0.25 (2/8) | NA | hu.MAP | View |
| 1798 | APOC3-GDPD1-APOA2-ORM2 | 4 | 0.50 (2/4) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE38941 | nomal_liver | HBV-associated_acute_liver_failure_liver | down | -2.59 | 4.38e-03 | Microarray data |
| GSE64605 | HS_unifected | HS_Q70_or_M91_infected | up | 4.65 | 1.31e-06 | Microarray data |
| GSE64605 | HS_unifected | HS_R70_or_L91_infected | up | 4.55 | 1.49e-06 | Microarray data |
| GSE97672-GPL16791 | MDM-418_H3N2_MOI0_18h | MDM-418_H3N2_MOI2_18h | up | 7.42 | 2.31e-03 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_18h | MDM-520_H5N1_MOI2_18h | up | 7.42 | 4.86e-02 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Tissue enriched:
| Tissue | Expression (TPM) |
|---|---|
| liver | 8677.3 |
| Ensembl ID: | ENSG00000110245 |
| Gene description: | Apolipoprotein C3 |
| Chromosome: | 11 |
| Position | 116829706-116833072 |
| Protein class: | Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Nucleoli, Cell Junctions |