P02652 (APOA2)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: APOA2_HUMAN

UniProtID: P02652

Gene name(s): APOA2

Protein name: Apolipoprotein A-II

Gene ID: 336

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P02652-P27958-PRO_0000037566HPIDB10498661two hybrid

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.050). Show
Machine learning evidence: yes (score 0.721).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
403CP-LF complex90.22 (2/9)NAhu.MAPView
517CP-MPO complex80.25 (2/8)NAhu.MAPView
1364CP-LF complex40.25 (1/4)NAhu.MAPView
1450GDPD1-APOA2-CFB-ORM240.25 (1/4)NAhu.MAPView
1598GDPD1-APOA2-ORM2-C340.25 (1/4)NAhu.MAPView
1765GDPD1-APOA2-ORM2-ORM140.25 (1/4)NAhu.MAPView
1798APOC3-GDPD1-APOA2-ORM240.50 (2/4)NAhu.MAPView
1823A1BG-GDPD1-APOA2-ORM240.25 (1/4)NAhu.MAPView
2310GDPD1-APOA2-ORM230.33 (1/3)NAhu.MAPView
3319APOA2-GDPD1-HP-ORM240.25 (1/4)NAhu.MAPView
3778ITIH2-GDPD1-APOA2-ORM240.25 (1/4)NAhu.MAPView
4087GDPD1-APOA2-HBD-ORM240.25 (1/4)NAhu.MAPView
4117GDPD1-APOA2-HBB-ORM240.25 (1/4)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE32155CRL-5800_unifectedCRL-1472_infecteddown-2.768.42e-03Microarray data
GSE38941nomal_liverHBV-associated_acute_liver_failure_liverdown-2.624.09e-02Microarray data
GSE97672-GPL16791MDM-315_H1N1_MOI0_18hMDM-315_H1N1_MOI2_18hup6.581.86e-02RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 0.0 Liver: 18325.0 Gallbladder: 0.0 Duodenum: 0.0 Rectum: 0.6 Tonsil: 0.3 Stomach: 1.7 Salivary glanda: 0.0 Adipose tissue: 2.1 Lung: 0.4 Lymph node: 0.3 Pancreas: 0.1 Kidney: 10.0 Colon: 0.7 Appendix: 1.1 Smooth musle: 0.0 Breast: 0.0 Parathyroid gland: 0.2 Esophagus: 0.0 Heart muscle: 0.0 Spleen: 0.9 Skeletal muscle: 0.0 Bone marrow: 17.1 Skin: 0.0 Urinary bladder: 0.7 Cervix, uterine: 0.0 Endometrium: 0.0 Ovary: 0.1 Fallopian tube: 0.0 Seminal vesicle: 0.0 Prostate: 0.6 Epididymis: 0.1 Testis: 1.3 Placenta: 1.9 Thyroid gland: 0.7 Cerebral cortex: 0.1 Adrenal gland: 0.1
Expression value is measured by Transcripts Per Million (TPM)
Tissue enriched:
TissueExpression (TPM)
liver 18325.0
Ensembl ID:ENSG00000158874
Gene description:Apolipoprotein A2
Chromosome:1
Position161222292-161223631
Protein class:Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Evidence:Evidence at protein level
Subcellular location: