Human protein: VAPB_HUMAN
UniProtID: O95292
Gene name(s): VAPB;UNQ484/PRO983
Protein name: Vesicle-associated membrane protein-associated protein B/C
Gene ID: 9217
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| O95292-P27958 | PHISTO,biogrid,HPIDB,VirusMentha | 22810585 | affinity chromatography technology,tandem affinity purification |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 6566 | SPG33-VAPB complex | 2 | 0.50 (1/2) | 21976701 | CORUM | View |
| 3999 | SPG33-VAPB complex | 2 | 1.00 (2/2) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE64677 | mock_infected_96h | m15_virus_infected_96h | down | -1.64 | 3.39e-12 | RNA-Seq data |
| GSE78711-GPL15520 | NPC_mock_infected | NPC_Zika_infected | down | -1.65 | 2.19e-18 | RNA-Seq data |
| GSE32140-GPL6947 | mock_for_influenza_2h | influenza_infection_2h | down | -1.53 | 4.91e-02 | Microarray data |
| GSE65123 | healthy_seronegative_control | HCV_infected | down | -2.42 | 4.55e-02 | Microarray data |
| GSE65574 | MCL001_mock_0h | MCL001_RFP-MERS_0h | down | -1.73 | 9.08e-03 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | down | -2.58 | 3.09e-05 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_RFP-MERS_12h | down | -1.69 | 2.21e-02 | Microarray data |
| GSE65574 | MCL001_mock_7h | MCL001_RFP-MERS_7h | down | -2.43 | 5.85e-04 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_NS1_1_118_infected_96h | up | 3.15 | 4.36e-04 | RNA-Seq data |
| GSE99298 | mock_infected_0h | hRSV_NS1_Y125A_infected_96h | up | 2.93 | 1.53e-02 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_12h | MDM-520_H5N1_MOI2_12h | down | -1.52 | 5.53e-06 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000124164 |
| Gene description: | VAMP associated protein B and C |
| Chromosome: | 20 |
| Position | 58389122-58451101 |
| Protein class: | Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Evidence: | Evidence at protein level |
| Subcellular location: | Endoplasmic reticulum |