O94966 (USP19)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: UBP19_HUMAN

UniProtID: O94966

Gene name(s): USP19;KIAA0891;ZMYND9

Protein name: Ubiquitin carboxyl-terminal hydrolase 19

Gene ID: 10869

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
O94966-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.282). Show
Machine learning evidence: yes (score 0.089).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
807OSBP-PDE4A-USP19-EEF2K-AGAP3-FKBP6-CDC37L170.14 (1/7)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE68673A549_uninfectedA549_infecteddown-1.975.04e-05RNA-Seq data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-1.651.82e-04Microarray data
GSE40711mock_infected_6hIDN3006_or_cl2PA_infected_6hdown-1.747.43e-05Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_NL219_pCalu3_24hdown-2.431.23e-05Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_VN1203_pCalu3_24hdown-2.411.18e-05Microarray data
GSE97672-GPL16791MDM-418_H3N2_MOI0_06hMDM-418_H3N2_MOI2_06hdown-1.751.76e-12RNA-Seq data
GSE97672-GPL16791MDM-513_H5N1_MOI0_06hMDM-513_H5N1_MOI2_06hdown-1.698.09e-13RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hdown-2.142.86e-30RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hdown-2.023.44e-23RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-2.725.53e-49RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_12hMDM-513_H5N1_MOI2_12hdown-2.059.31e-22RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 21.8 Liver: 6.9 Gallbladder: 23.0 Duodenum: 20.0 Rectum: 15.7 Tonsil: 13.9 Stomach: 15.6 Salivary glanda: 11.7 Adipose tissue: 19.5 Lung: 24.3 Lymph node: 23.7 Pancreas: 4.1 Kidney: 16.7 Colon: 16.7 Appendix: 24.1 Smooth musle: 26.0 Breast: 17.3 Parathyroid gland: 45.7 Esophagus: 18.3 Heart muscle: 16.2 Spleen: 28.2 Skeletal muscle: 22.9 Bone marrow: 16.0 Skin: 29.7 Urinary bladder: 19.0 Cervix, uterine: 23.5 Endometrium: 29.1 Ovary: 25.2 Fallopian tube: 36.1 Seminal vesicle: 30.9 Prostate: 27.9 Epididymis: 22.0 Testis: 32.7 Placenta: 21.3 Thyroid gland: 33.8 Cerebral cortex: 25.3 Adrenal gland: 24.9
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000172046
Gene description:Ubiquitin specific peptidase 19
Chromosome:3
Position49108046-49120938
Protein class:Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Evidence:Evidence at protein level
Subcellular location: