O75937 (DNAJC8)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: DNJC8_HUMAN

UniProtID: O75937

Gene name(s): DNAJC8;SPF31;HSPC315;HSPC331

Protein name: DnaJ homolog subfamily C member 8

Gene ID: 22826

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
O75937-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.719).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
275517S U2 snRNP330.09 (3/33)12234937CORUMView
351Spliceosome1430.04 (6/143)12226669CORUMView
2440DNAJC8-ZNF207-PIN430.67 (2/3)NAhu.MAPView
3573CUTC-DNAJC8-ZNF207-PIN440.50 (2/4)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hdown-1.731.37e-10RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-1.571.33e-08RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 46.5 Liver: 28.8 Gallbladder: 66.5 Duodenum: 43.7 Rectum: 51.7 Tonsil: 77.7 Stomach: 36.3 Salivary glanda: 17.6 Adipose tissue: 60.8 Lung: 66.9 Lymph node: 93.5 Pancreas: 6.0 Kidney: 57.4 Colon: 46.7 Appendix: 75.7 Smooth musle: 92.0 Breast: 63.9 Parathyroid gland: 57.5 Esophagus: 50.4 Heart muscle: 39.1 Spleen: 75.2 Skeletal muscle: 18.0 Bone marrow: 38.3 Skin: 49.6 Urinary bladder: 61.7 Cervix, uterine: 70.0 Endometrium: 93.4 Ovary: 68.0 Fallopian tube: 69.9 Seminal vesicle: 64.3 Prostate: 71.8 Epididymis: 56.6 Testis: 51.5 Placenta: 88.5 Thyroid gland: 90.2 Cerebral cortex: 72.6 Adrenal gland: 64.3
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000126698
Gene description:DnaJ heat shock protein family (Hsp40) member C8
Chromosome:1
Position28199456-28233025
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm