HVIDB-PPI detail

O15205 (UBD)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Interaction information
PPI score
DEGs post infections
Tissue specific expression

Human protein: UBD_HUMAN

UniProtID: O15205

Gene name(s): UBD;FAT10

Protein name: Ubiquitin D

Gene ID: 10537

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
O15205-P27958	PHISTO	23487458	protein array

Evidence suggesting a protein interaction:

Interolog evidence:	none/insignificant.
DDI evidence:	yes (score 0.002).	Show
Machine learning evidence:	yes (score 0.097).

Combined Score: 0.062

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE72925	Normal	PVAN	up	1.96	6.67e-05	Microarray data
GSE11348	2d_Postinfection_control	2d_Postinfection_RV16	up	2.21	1.37e-03	Microarray data
GSE13637	HUVEC_control	PR8-infected_pEGZ-transfected_HUVEC	up	2.52	3.39e-05	Microarray data
GSE1377	uninfected_control	KSHV_infected	up	2.34	4.34e-02	Microarray data
GSE24238	Mock_24h	HCMV_24h	up	2.08	1.62e-02	Microarray data
GSE30723	ATII_control_24h	ATII_PR8_24h	up	3.88	9.67e-03	Microarray data
GSE31524	H5N2-F59_Mock_infection	H5N2-F59_infection_10h	up	1.72	4.44e-06	Microarray data
GSE31524	H5N3_Mock_infection	H5N3_infection_10h	up	3.15	4.01e-07	Microarray data
GSE32140-GPL6480	mock_for_influenza_2h	influenza_infection	up	2.36	2.56e-03	Microarray data
GSE32140-GPL6947	mock_for_RSV_2h	RSV_infection_2h	up	2.53	1.64e-02	Microarray data
GSE32155	CRL-5800_unifected	CRL-1472_infected	up	5.13	4.75e-04	Microarray data
GSE32155	CRL-5810_unifected	CRL-1472_infected	up	4.81	5.94e-04	Microarray data
GSE38941	nomal_liver	HBV-associated_acute_liver_failure_liver	up	2.71	1.62e-06	Microarray data
GSE40711	mock_infected_6h	IDN3006_or_cl2PA_infected_6h	up	3.12	6.63e-04	Microarray data
GSE47865	mock_infected	SV_infected	up	2.54	3.82e-10	Microarray data
GSE49628	Bcells_Quiescent	Bcells_EBV_transformed	up	4.53	8.43e-06	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_NL219_pCalu3_24h	up	2.23	5.24e-06	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_Pan99_pCalu3_24h	up	4.78	1.09e-07	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_VN1203_pCalu3_24h	up	2.43	1.08e-06	Microarray data
GSE64605	HS_unifected	HS_Q70_or_M91_infected	up	2.78	3.75e-06	Microarray data
GSE64605	HS_unifected	HS_R70_or_L91_infected	up	3.14	7.70e-06	Microarray data
GSE65574	MCL001_mock_24h	MCL001_d3-5-MERS_24h	up	1.72	5.82e-04	Microarray data
GSE65574	MCL001_mock_24h	MCL001_d4B-MERS_24h	up	2.42	1.94e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_dNSP16-MERS_24h	up	2.12	1.80e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_icMERS_24h	up	3.13	4.92e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_RFP-MERS_24h	up	2.79	6.10e-03	Microarray data
GSE66486	PBMC_uninfected_control	PBMC_healthy_donor_infected_16h	up	5.32	1.52e-03	Microarray data
GSE66486	PBMC_uninfected_control	PBMC_healthy_donor_infected_8h	up	3.88	4.39e-03	Microarray data
GSE980	monocyte-derived_dendritic_cells_control	MV-infected_dendritic_cells_24h	up	2.40	6.80e-03	Microarray data
GSE99858	PBMC_control	PBMC_RV16_infection	up	1.74	7.73e-04	Microarray data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Tissue enhanced:

Tissue	Expression (TPM)
lymph node	94.9
tonsil	92.5

Ensembl ID:	ENSG00000213886
Gene description:	Ubiquitin D
Chromosome:	6
Position	29555515-29559925
Protein class:	Predicted intracellular proteins
Evidence:	Evidence at protein level
Subcellular location:	Nucleus, Nucleoli fibrillar center