O14602 (EIF1AY)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: IF1AY_HUMAN

UniProtID: O14602

Gene name(s): EIF1AY

Protein name: Eukaryotic translation initiation factor 1A

Gene ID: 9086

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
O14602-P27958PHISTO23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: yes (score 0.009). Show
Machine learning evidence: yes (score 0.125).
Combined Score: 0.125


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1814RPS26-EIF1AY20.50 (1/2)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_18hVN1203_infected_18hup2.054.76e-02Microarray data
GSE32155CRL-5800_unifectedCRL-5807_infectedup5.004.67e-07Microarray data
GSE32155CRL-5810_unifectedCRL-5807_infectedup4.351.13e-06Microarray data
GSE32155HTB-4_unifectedHTB-174_infectedup3.031.71e-04Microarray data
GSE38900-GPL6884Dallas_healthy_matched_controlDallas_HRV_acute_infectionup3.671.58e-03Microarray data
GSE38900-GPL6884Dallas_healthy_matched_controlDallas_influenza_A_infectiondown-3.599.87e-03Microarray data

Human tissue specific expression (TPM)

Small intestine: 31.9 Liver: 12.6 Gallbladder: 13.2 Duodenum: 14.3 Rectum: 27.1 Tonsil: 23.7 Stomach: 9.8 Salivary glanda: 1.9 Adipose tissue: 0.2 Lung: 7.9 Lymph node: 12.5 Pancreas: 1.9 Kidney: 12.4 Colon: 13.3 Appendix: 15.3 Smooth musle: 0.0 Breast: 0.2 Parathyroid gland: 0.3 Esophagus: 14.2 Heart muscle: 19.8 Spleen: 21.2 Skeletal muscle: 15.3 Bone marrow: 33.7 Skin: 4.9 Urinary bladder: 16.4 Cervix, uterine: 0.0 Endometrium: 0.1 Ovary: 0.0 Fallopian tube: 0.0 Seminal vesicle: 27.2 Prostate: 42.2 Epididymis: 24.0 Testis: 39.6 Placenta: 23.3 Thyroid gland: 7.3 Cerebral cortex: 18.2 Adrenal gland: 0.0
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000198692
Gene description:Eukaryotic translation initiation factor 1A, Y-linked
Chromosome:Y
Position20575725-20593154
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Cytosol