gene detail

Gene description

RAP-DB: OS11G0484400

Short description: Similar to bifunctional dihydrofolate reductase-thymidylate synthase.

Orthologous

Arabidopsis: No orthologous

Maize:

GRMZM2G005990

Wheat: No orthologous

GO biological process

dTMP biosynthetic process (GO:0006231), glycine biosynthetic process (GO:0006545), one-carbon metabolic process (GO:0006730), nucleotide biosynthetic process (GO:0009165), oxidation-reduction process (GO:0055114)

GO cellular component

unknown

GO molecular function

dihydrofolate reductase activity (GO:0004146), thymidylate synthase activity (GO:0004799), oxidoreductase activity (GO:0016491)

Protein domain

Pfam	PF00186, Dihydrofolate reductase
Pfam	PF00303, Thymidylate synthase

Metabolic pathway

PWY-7211: superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
PWY0-166: superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
PWY-7199: pyrimidine deoxyribonucleosides salvage
PWY-7187: pyrimidine deoxyribonucleotides de novo biosynthesis II
PWY-3841: folate transformations II
PWY-7184: pyrimidine deoxyribonucleotides de novo biosynthesis I
PWY-7200: superpathway of pyrimidine deoxyribonucleoside salvage

KEGG pathway

PATH:dosa00240: Pyrimidine metabolism
PATH:dosa00790: Folate biosynthesis
PATH:dosa00670: One carbon pool by folate

Coexpression network

GSE62894_S_77  view
GSE63047_T7174R  view
GSE62893_S_15B  view
GSE62894_R_77  view

Differentially expressed condition

1 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE62894	Nipponbare, pish, water 5 d	Nipponbare, pish, Magnaporthe oryzae Kyu77-07A 5 d	-3.01	1.09E-07