gene detail

Gene description

Short description: Similar to Phosphoribosylformylglycinamidine cyclo-ligase, chloroplast/mitochondrial precursor (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase) (VUpur5).

Orthologous

Arabidopsis:

AT3G55010

Maize:

GRMZM2G160925

Wheat:

TA.2335.1.S1_AT

GO biological process

'de novo' IMP biosynthetic process (GO:0006189)

GO cellular component

cytoplasm (GO:0005737)

GO molecular function

catalytic activity (GO:0003824), phosphoribosylformylglycinamidine cyclo-ligase activity (GO:0004641)

Protein domain

Pfam	PF00586, AIR synthase related protein, N-terminal domain
Pfam	PF02769, AIR synthase related protein, C-terminal domain

Metabolic pathway

PWY-6121: 5-aminoimidazole ribonucleotide biosynthesis I
PWY-841: superpathway of purine nucleotides de novo biosynthesis I

KEGG pathway

PATH:dosa00230: Purine metabolism

Coexpression network

GSE62894_S_77  view
GSE63047_T7174R  view
GSE62893_S_15B  view
GSE62893_R_15B  view
GSE63047_DELTAHRCV  view

Differentially expressed condition

4 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE62894	Nipponbare, Pish, water 2 d	Nipponbare, Pish, Magnaporthe oryzae Kyu77-07A 2 d	2.11	1.20E-03
GSE62894	Nipponbare, pish, water 2 d	Nipponbare, pish, Magnaporthe oryzae Kyu77-07A 2 d	1.52	3.66E-02
GSE62894	Nipponbare, pish, water 3 d	Nipponbare, pish, Magnaporthe oryzae Kyu77-07A 3 d	1.92	2.94E-03
GSE62894	Nipponbare, pish, water 5 d	Nipponbare, pish, Magnaporthe oryzae Kyu77-07A 5 d	-2.58	1.34E-05