gene detail

Gene description

RAP-DB: OS03G0655700

Short description: Similar to 3-isopropylmalate dehydrogenase 2.

Orthologous

Arabidopsis:

AT5G03290

Maize:

GRMZM5G803490

Wheat: No orthologous

GO biological process

leucine biosynthetic process (GO:0009098), oxidation-reduction process (GO:0055114)

GO cellular component

cytoplasm (GO:0005737)

GO molecular function

magnesium ion binding (GO:0000287), 3-isopropylmalate dehydrogenase activity (GO:0003862), oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616), NAD binding (GO:0051287)

Protein domain

Pfam	PF00180, Isocitrate/isopropylmalate dehydrogenase
SMART	SM01329, Iso_dh

Metabolic pathway

LEUSYN-PWY: leucine biosynthesis
BRANCHED-CHAIN-AA-SYN-PWY: superpathway of leucine, valine, and isoleucine biosynthesis

KEGG pathway

PATH:dosa01210: 2-Oxocarboxylic acid metabolism
PATH:dosa01230: Biosynthesis of amino acids
PATH:dosa00660: C5-Branched dibasic acid metabolism
PATH:dosa00290: Valine, leucine and isoleucine biosynthesis

Coexpression network

GSE63047_T7174R  view
GSE33411_IRBB5  view
GSE16793_XOO  view
GSE16793_XOC  view
GSE62894_S_77  view
GSE33411_IRBB7  view
GSE62893_S_15B  view
GSE62894_R_77  view
GSE33411_IR24  view
GSE63047_DELTAHRCV  view

Differentially expressed condition

4 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE62894	Nipponbare, pish, water 5 d	Nipponbare, pish, Magnaporthe oryzae Kyu77-07A 5 d	-4.56	6.43E-10
GSE62895	Nipponbare, Pia, water 3 d	Nipponbare, Pia, Magnaporthe oryzae P91-15B 3 d	-1.62	5.04E-03
GSE62895	Nipponbare, pia, water 3 d	Nipponbare, pia, Magnaporthe oryzae P91-15B 3 d	-1.80	2.32E-03
GSE62895	Nipponbare, pia, water 5 d	Nipponbare, pia, Magnaporthe oryzae P91-15B 5 d	-1.94	1.96E-03