gene detail

Gene description

Short description: Similar to 3-isopropylmalate dehydrogenase, chloroplast precursor (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH).

Orthologous

Arabidopsis:

AT5G03290

Maize:

GRMZM2G018566 GRMZM2G120857

Wheat: No orthologous

GO biological process

tricarboxylic acid cycle (GO:0006099), oxidation-reduction process (GO:0055114)

GO cellular component

unknown

GO molecular function

magnesium ion binding (GO:0000287), isocitrate dehydrogenase (NAD+) activity (GO:0004449), oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616), NAD binding (GO:0051287)

Protein domain

Pfam	PF00180, Isocitrate/isopropylmalate dehydrogenase
SMART	SM01329, Iso_dh

Metabolic pathway

PWY-6549: glutamine biosynthesis III
PWY-5690: TCA cycle II (plants and fungi)
PWY-5464: superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle

KEGG pathway

PATH:dosa01200: Carbon metabolism
PATH:dosa01210: 2-Oxocarboxylic acid metabolism
PATH:dosa01230: Biosynthesis of amino acids
PATH:dosa00020: Citrate cycle (TCA cycle)

Coexpression network

GSE62895_S_15B_ROOT  view
GSE63047_T7174R  view
GSE62895_R_15B_ROOT  view
GSE62894_R_77  view
GSE63047_DELTAHRCV  view

Differentially expressed condition

1 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE62893	Nipponbare, pia, water 3 d	Nipponbare, pia, Magnaporthe oryzae P91-15B 3 d	1.80	2.93E-03