gene detail

Gene description

TAIR ID: AT1G51660

Short description: mitogen-activated protein kinase kinase 4

Pathogen responsiveness: 0.96

General responsiveness: -1.89

Orthologous

Rice:

OS02G0787300 OS06G0147800 OS06G0473200

Maize: No orthologous gene

Wheat: No orthologous gene

GO biological process

plant-type hypersensitive response, stress-activated protein kinase signaling cascade, activation of MAPK activity, regulation of stomatal complex development, MAPK cascade, regulation of mitotic cell cycle, floral organ abscission, defense response, incompatible interaction, regulation of stomatal complex patterning, inflorescence development, protein phosphorylation

GO cellular component

nucleus, chloroplast stroma, cytoplasm

GO molecular function

MAP kinase kinase activity, protein serine/threonine kinase activity, ATP binding, protein binding, kinase activity

Protein domain

Pfam	PF00069, Protein kinase domain
SMART	SM00220, S_TKc

Metabolic pathway

Not involved in metabolic pathway

KEGG pathway

PATH:ath04016: MAPK signaling pathway - plant
PATH:ath04075: Plant hormone signal transduction
PATH:ath04626: Plant-pathogen interaction

Transcriptional regulation

Regulator:
AT5G13790, AT4G16110, AT2G22300

Target:
none

Protein-protein interaction network

The number of partners (degree) is: 14 (Top20%)

click to view PPI network

Coexpression network

GSE45212_WT_PSTDC3000_AVRRPT2  view
GSE13739_WT_GO  view
GSE13739_EDS16_GO  view
GSE5686_WT_GO  view
GSE56094_WT_PSTDC3000  view
GSE45212_MED14_PSTDC3000_AVRRPT2  view

Differentially expressed condition

30 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE12856	Col, WT, control	Col, WT, Bg h	1.77	2.64E-07
GSE12856	Col, ataf1, control	Col, ataf1, Bg h	2.53	8.18E-09
GSE17464	Laer, JA+Flg22 0 h	Laer, JA+Flg22 1 h	1.91	2.85E-03
GSE17464	Laer, control	Laer, Flg22 1 h	2.25	9.31E-05
GSE17464	Penta, control	Penta, Flg22 2 h	2.49	1.70E-05
GSE17500	Col, WT, control 0 h	Col, WT, PstDC3000 24 h	1.50	4.62E-05
GSE18978	Col, WT, control 24 h	Col, WT, PsmES4326 24 h	1.99	1.24E-07
GSE2538	Col, WT, control	Col, WT, crab shell chitin 30 min	2.18	5.49E-04
GSE2538	Col, WT, control	Col, WT, purified chitin octamer 30 min	1.93	1.33E-03
GSE40544	Col, WT, control	Col, WT, PstDC3000 EV	1.52	1.22E-04
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 12 h	3.30	1.05E-13
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 4 h	2.48	2.57E-11
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 8 h	3.75	2.99E-14
GSE45212	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 12 h	3.20	1.80E-13
GSE45212	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 4 h	4.86	8.11E-16
GSE45212	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 8 h	4.02	7.28E-15
GSE45214	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 4 h	4.63	4.33E-14
GSE45214	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 4 h	3.35	5.29E-12
GSE45214	Col, med16, PstDC3000 AvrRpt2 0 h	Col, med16, PstDC3000 AvrRpt2 4 h	4.86	7.40E-15
GSE45214	Col, npr1, PstDC3000 AvrRpt2 0 h	Col, npr1, PstDC3000 AvrRpt2 4 h	4.23	2.00E-13
GSE4746	Col, WT, water 30 min	Col, WT, chitooctaose 30 min	1.95	2.12E-04
GSE50526	Col, WT, mock 9 h	Col, WT, A. brassicicola 9 h	1.92	4.58E-04
GSE5520	Col, WT, control 10 h	Col, WT, Cor- 10 h	2.15	3.68E-05
GSE5616	Col, WT, water 6 h	Col, WT, P. infestans 6 h	2.01	2.61E-06
GSE58954	Col, WT, Psm AvrRpt2 0 h	Col, WT, Psm AvrRpt2 6 h	2.67	9.78E-04
GSE8319	Col, WT, control	Col, WT, chitooctaose 30 min	2.62	1.03E-14
GSE9674	Ws-4, AtMYB30 ox, control	Ws-4, AtMYB30 ox, Xanthomonas strain Xcc147 2-4 h	1.95	1.72E-05
GSE9674	Ws-4, AtMYB30 ox, control	Ws-4, AtMYB30 ox, Xanthomonas strain Xcc147 6 h	2.91	2.57E-06
GSE9674	Ws-4, WT, control	Ws-4, WT, Xanthomonas strain Xcc147 2-4 h	1.98	2.17E-05
GSE9674	Ws-4, WT, control	Ws-4, WT, Xanthomonas strain Xcc147 6 h	3.14	2.01E-06