Accession: YPR169W - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = YPR169W (Len=492)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (YPR169W, Len=492):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAKSKKKTDVVDSTNLPILELLSLKAPIFQSLLHPELPIIITGFGTGHIVCHRYDPAKLQSHLDRRRRIDTATTGKDAKK 80  
WD40-rpts                    (_________________WD 1________________)                           

Query       81 GVCPWIRLDIDLETGDLKFVDIEEQQQQKQTGKDEDLGVKTLWKTKRHKGSVRAMCFDSKGDNIFSVGSDNVLKKANTMT 160 
WD40-rpts                                (_______________________WD 2______________________)   

Query      161 GKVVKKVNLSSLFNSEEKKNDKFTKLCASQTHPFILIGDESGNIHVINSENLALSNSIRSIHFGDSINDIFHFDKRSAYK 240 
WD40-rpts              (_________________WD 3_________________)   (__________________WD 4______

Query      241 FISLGQTTLAYFDVRDKDAKPNVAGNEDGKILISDDQEDEVLCGCFVDPEVADTLLCGMGEGIVTVWKPNKNDLEDQMSR 320 
WD40-rpts      ____________)   (_______________________WD 5_______________________)       (____

Query      321 IKISKDESIDCIVPTLQDDNCVWCGCSNGNIYKVNAKLGKVVEIRNHSELDEVSFVDLDFEYRVVSGGLENIKIWELSSD 400 
WD40-rpts      _____________WD 6_________________)(__________________WD 7_________________)   (

Query      401 DVEENASVESDSDEPLSHSDEDLSDDTSSDDETTLVGLSKEELLDELDKDLKEDHQEEKESNSKSVKKRKIMKENNKKKD 480 
WD40-rpts      _________________WD 8________________)                                          

Query      481 LYEHGIKKFDDL 492 
WD40-rpts

8 WD40-repeats found in QUERY=YPR169W (Len=492):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  2    15-53       7.55  426.58  0.00011       12.5%     52.36
  WD 2:  Seg  7   107-157      7.87  439.76  7.4e-05       20.0%     57.29
  WD 3:  Seg 12   169-208      9.45  505.20  9.7e-06       17.5%     46.49
  WD 4:  Seg 15   212-253      4.64  306.13  0.00465        7.5%     54.67
  WD 5:  Seg 19   257-308      6.03  363.95  0.00077       20.0%     38.52
  WD 6:  Seg 23   316-355      5.92  359.19  0.00090       15.0%     50.37
  WD 7:  Seg 27   356-396      4.08  283.26  0.00945       15.0%     49.71
  WD 8:  Seg 28   400-438      4.73  310.23  0.00410       17.5%      8.87

Multiple sequence alignment of 8 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   15-53     -NL-----------PILELLS--LKAPIFQ-SL-------------LHPELPIIITGFGTGHIVCHR
   WD 2  107-157    QQKQTGKDEDLGVKTLWKTKR--HKGSVRA-MC-------------FDSKGDNIFSVGSDNVLKKAN
   WD 3  169-208    LSS-----------LFNSEEK--KNDKFTK-LC-------------ASQTHPFILIGDESGNIHVIN
   WD 4  212-253    -LA-----------LSNSIRSIHFGDSIND-IF------------HFDKRSAYKFISLGQTTLAYFD
   WD 5  257-308    -KD-----------AKPNVAG--NEDGKIL-ISDDQEDEVLCGCFVDPEVADTLLCGMGEGIVTVWK
   WD 6  316-355    -DQ-----------MSRIKIS--KDESIDCIVP-------------TLQDDNCVWCGCSNGNIYKVN
   WD 7  356-396    AKL----------GKVVEIRN--HSELDEV-SF-------------VDLDFEYRVVSGGLENIKIWE
   WD 8  400-438    -DD-----------VEENASV--ESDSDEP-LS-------------HSDEDLSDDTSSDDETTLVGL

   WD40 Template    TGE-----------CLRTLSG--HTSGVTS-VS-------------FSPDGKRLVSGSEDGTIKVWD