WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000426154 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000426154 (Len=1231) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000426154, Len=1231): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKH 80
WD40-rpts (__________________WD 1__________________) (
Query 81 KQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIV 160
WD40-rpts __________________WD 2_________________) (__________________WD 3______________
Query 161 NVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACG 240
WD40-rpts ___) (________________WD 4________________)
Query 241 RGKKADSTFCITSSGLLCEFSDRRLLDKWVELRTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDI 320
WD40-rpts (_________________WD 5_________________)
Query 321 ASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQ 400
WD40-rpts (___________________WD 6___________________)(_________________________WD 7____
Query 401 ACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVC 480
WD40-rpts ____________________) (_____________WD 8____________) (_________________
Query 481 VSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEH 560
WD40-rpts WD 9________________) (__________________WD10__________________)(_____________
Query 561 SSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNIS 640
WD40-rpts _______WD11___________________) (___________________WD12__________________)(_
Query 641 SGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSC 720
WD40-rpts ___________________WD13___________________) (_________________WD14____________
Query 721 IFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVL 800
WD40-rpts ____)
Query 801 AKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPS 880
WD40-rpts
Query 881 QDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMD 960
WD40-rpts
Query 961 TSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEE 1040
WD40-rpts
Query 1041 EGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRP 1120
WD40-rpts
Query 1121 AQVPQASEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSPGSSP 1200
WD40-rpts
Query 1201 GAVGAEQTQALLEQYSELLLRAVERRMERKL 1231
WD40-rpts
 14 WD40-repeats found in QUERY=ENSP00000426154 (Len=1231): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 4 35-76 4.49 300.20 0.00559 10.0% 47.89 WD 2: Seg 8 80-120 7.63 429.65 0.00010 35.0% 56.99 WD 3: Seg 12 124-164 7.73 434.17 8.8e-05 35.0% 56.02 WD 4: Seg 16 167-204 6.23 371.87 0.00061 30.0% 53.34 WD 5: Seg 24 261-300 7.17 410.82 0.00018 15.0% 50.27 WD 6: Seg 30 323-366 7.08 407.19 0.00020 30.0% 52.61 WD 7: Seg 34 367-421 6.20 370.65 0.00063 30.0% 52.77 WD 8: Seg 38 427-457 2.78 229.46 0.04918 10.0% 40.47 WD 9: Seg 40 463-501 7.78 436.00 8.3e-05 32.5% 52.18 WD10: Seg 44 505-546 7.05 405.89 0.00021 27.5% 56.88 WD11: Seg 48 547-591 7.09 407.50 0.00020 30.0% 53.35 WD12: Seg 52 596-638 6.34 376.66 0.00052 17.5% 55.97 WD13: Seg 56 639-683 7.23 413.27 0.00017 15.0% 53.49 WD14: Seg 60 687-725 9.81 520.06 6.1e-06 47.5% 57.73Multiple sequence alignment of 14 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 35-76 LS-----S--KVTLEKVLGI----T----VSGGRGLACDPRS---G----------LVAYPA---G--CVVVLFN WD 2 80-120 -H-----K-----QHHILNS----S----RKTITALAFSPDG---K----------YLVTGE--SGHMPAVRVWD WD 3 124-164 -H-----S-----QVAELQE----H----KYGVACVAFSPSA---K----------YIVSVGYQHD--MIVNVWA WD 4 167-204 -K-----N-----IVVASNK----V----SSRVTAVSFSEDC---S----------YFVTAG---N--RHIKFWY WD 5 261-300 SD-----R-----RLLDKWV----E----LRTTVAHCISVSQ---D----------YIFCGC--AD--GTVRLFN WD 6 323-366 VT-----E-----ASRLFSGVANAR----YPDTIALTFDPTN---Q----------WLSCVY--ND--HSIYVWD WD 7 367-421 VR-----DPKKVGKVYSALY----H----SSCVWSVEVYPEV---KDSNQACLPPSSFITCS--SD--NTIRLWN WD 8 427-457 -------------------V----H----GSTLHRNILSSDL---I----------KIIYVD--GN--TQALLDT WD 9 463-501 -D-----K-----ADASLLD----P----RVGIRSVCVSPNG---Q----------HLASGD--RM--GTLRVHE WD10 505-546 -L-----S-----EMLKVEA----H----DSEILCLEYSKPDTGLK----------LLASAS--RD--RLIHVLD WD11 547-591 AG--REYS-----LQQTLDE----H----SSSITAVKFAASD---G--------QVRMISCG--AD--KSIYFRT WD12 596-638 -G-----D-----GVQFTRT----HHVVRKTTLYDMDVEPSW---K----------YTAIGC--QD--RNIRIFN WD13 639-683 ISSGKQKK-----LFKGSQG----E----DGTLIKVQTDPSG---I----------YIATSC--SD--KNLSIFD WD14 687-725 -G-----E-----CVATMFG----H----SEIVTGMKFSNDC---K----------HLISVS--GD--SCIFVWR WD40 Template TG-----E-----CLRTLSG----H----TSGVTSVSFSPDG---K----------RLVSGS--ED--GTIKVWD |
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