Accession: ENSP00000408578 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000408578 (Len=345)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000408578, Len=345):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MHERFIHCFCIDWAPKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFES 80  
WD40-rpts      (______________WD 1_____________)     (_________________WD 2________________) (_

Query       81 ENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWV 160 
WD40-rpts      ___________________WD 3___________________)                            (________

Query      161 HGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLD 240 
WD40-rpts      ______WD 4______________)   (________________WD 5________________) (____________

Query      241 IPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKEPSRHGLPQ 320 
WD40-rpts      _____WD 6_________________)(__________________WD 7__________________)           

Query      321 LPGGAHQLPRLEQGPHPDCHLPQQP 345 
WD40-rpts

7 WD40-repeats found in QUERY=ENSP00000408578 (Len=345):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     1-33       7.48  423.71  0.00012       15.0%     43.26
  WD 2:  Seg  4    39-77       7.23  413.32  0.00017       20.0%     53.59
  WD 3:  Seg  8    79-123      8.23  454.78  4.6e-05       25.0%     53.80
  WD 4:  Seg 13   152-185      7.90  440.87  7.1e-05       40.0%     49.82
  WD 5:  Seg 16   189-226      6.68  390.70  0.00034       20.0%     52.66
  WD 6:  Seg 20   228-267      2.94  236.21  0.04007        7.5%     19.20
  WD 7:  Seg 22   268-309      6.84  397.01  0.00028       27.5%     49.79

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    1-33     ------------MHERFIHCFCIDWAPKSD----RIV-----TCGADRNAYVWS
   WD 2   39-77     -WK-----PTLVILRINRAATFVKWSPLEN----KFA-----VGSGARLISVCY
   WD 3   79-123    ESENDWWVSKHIKKPIRSTVLSLDWHPNNV----LLA-----AGSCDFKCRVFS
   WD 4  152-185    GG-----------SGTGGWVHGVSFSASGS----RLA-----WVSHDSTVSVAD
   WD 5  189-226    -SV-----QVSTLKTEFLPLLSVSFVSENS----VVA-----AGH-DCCPMLFN
   WD 6  228-267    DDR-----GCLTFVSKLDIPKQSIQRNM---------SAMERFRNMDKRATTED
   WD 7  268-309    RNT-----ALET--LHQNSITQVSIYEVDKQDCRKFC-----TTGIDGAMTIWD

   WD40 Template    TGE-----CLRTLSGHTSGVTSVSFSPDGK----RLV-----SGSEDGTIKVWD