Accession: ENSP00000392270 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000392270 (Len=350)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000392270, Len=350):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAAD 80  
WD40-rpts        (___________________WD 1__________________)   (_________________WD 2__________

Query       81 FTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS 160 
WD40-rpts      ______)   (________________WD 3________________)(__________________WD 4_________

Query      161 ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVA 240 
WD40-rpts      _________)   (________________WD 5_______________)   (________________WD 6______

Query      241 GGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKI 320 
WD40-rpts      __________)   (_________________WD 7________________)                           

Query      321 GFPETTEEELEEIASENSDCIFPSAPDVKA 350 
WD40-rpts

7 WD40-repeats found in QUERY=ENSP00000392270 (Len=350):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     3-45       8.50  465.87  3.3e-05       35.0%     50.89
  WD 2:  Seg  5    49-87       9.70  515.54  7.0e-06       30.0%     53.66
  WD 3:  Seg  9    91-128      8.44  463.20  3.6e-05       32.5%     56.37
  WD 4:  Seg 13   129-170      8.07  447.81  5.7e-05       30.0%     49.07
  WD 5:  Seg 17   174-210      5.41  338.12  0.00173       22.5%     52.60
  WD 6:  Seg 21   214-251      7.76  435.10  8.5e-05       22.5%     52.55
  WD 7:  Seg 25   255-293     10.63  553.85  2.1e-06       47.5%     53.47

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    3-45     MRQ---TPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQ
   WD 2   49-87     -GD---WIGTFLGHKGAVWGATLN---KDATKAATAAADFTAKVWD
   WD 3   91-128    -GD---ELMTL-AHKHIVKTVDFT---QDSNYLLTGGQDKLLRIYD
   WD 4  129-170    LNKPEAEPKEISGHTSGIKKALWC---SEDKQILSAD-DKTVRLWD
   WD 5  174-210    -MT---EVKSLNFNMS-VSSMEYI---PEGEILVITY-GRSIAFHS
   WD 6  214-251    -LD---PIKSFEAPAT-INSASLH---PEKEFLVAGGEDFKLYKYD
   WD 7  255-293    -GE---ELESYKGHFGPIHCVRFS---PDGELYASGSEDGTLRLWQ

   WD40 Template    TGE---CLRTLSGHTSGVTSVSFS---PDGKRLVSGSEDGTIKVWD