Accession: ENSP00000377933 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000377933 (Len=443)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000377933, Len=443):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEF 80  
WD40-rpts                   (_________________WD 1________________)                      (_____

Query       81 DYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMV 160 
WD40-rpts      _______________WD 2___________________)                                         

Query      161 EATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVY 240 
WD40-rpts           (_______________WD 3______________)            (_________________WD 4______

Query      241 SSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQ 320 
WD40-rpts      __________)                   (________________WD 5________________)            

Query      321 VHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRR 400 
WD40-rpts        (___________________WD 6___________________)   (_________________WD 7_________

Query      401 KDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN 443 
WD40-rpts      _______)

7 WD40-repeats found in QUERY=ENSP00000377933 (Len=443):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1    14-52       7.61  428.95  0.00010       15.0%     42.25
  WD 2:  Seg  5    75-119      4.47  299.28  0.00575       15.0%     44.05
  WD 3:  Seg 12   166-200      5.92  359.09  0.00090       22.5%     46.32
  WD 4:  Seg 16   213-251      6.20  370.57  0.00063       25.0%     39.65
  WD 5:  Seg 20   271-308      6.69  390.81  0.00034       27.5%     41.16
  WD 6:  Seg 24   323-366      5.41  337.98  0.00173       10.0%     43.49
  WD 7:  Seg 27   370-408      4.95  319.33  0.00309        7.5%     24.38

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   14-52     -FLRDHSY---ATEAD----IISTVEFNH--TGELLATGDKGGRVVIFQ
   WD 2   75-119    SHEPEFDYLKSLEIEE----KINKIRWLPQQNAAYFLLSTNDKTVKLWK
   WD 3  166-200    ----RVFA---NAHTY----HINSISVNS--DYETYMS-ADDLRINLWN
   WD 4  213-251    IKP--ANM---EELTE----VITAAEFHP-HHCNTFVYSSSKGTIRLCD
   WD 5  271-308    -PSNRSFF---SEIIS----SISDVKFSH--SGRYIMTRD-YLTVKVWD
   WD 6  323-366    DYLRSKLC---SLYENDCIFDKFECVWNG--SDSVIMTGSYNNFFRMFD
   WD 7  370-408    -KRDVTLE---ASREN----SKPRAILKP--RKVCVGGKRRKDEISVDS

   WD40 Template    TGECLRTL---SGHTS----GVTSVSFSP--DGKRLVSGSEDGTIKVWD