Accession: ENSP00000377931 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000377931 (Len=422)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000377931, Len=422):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 QKTDIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQ 80  
WD40-rpts      (_____________WD 1____________)                       (___________________WD 2__

Query       81 NAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISV 160 
WD40-rpts      _________________)                                  (_____________________WD 3__

Query      161 NSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRH 240 
WD40-rpts      __________________)            (_________________WD 4________________)          

Query      241 TKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDK 320 
WD40-rpts               (________________WD 5________________)              (__________________

Query      321 FECVWNGSDSVIMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKILHTAWH 400 
WD40-rpts      _WD 6___________________)   (_________________WD 7________________)             

Query      401 PSENIIAVAATNNLYIFQDKVN 422 
WD40-rpts

7 WD40-repeats found in QUERY=ENSP00000377931 (Len=422):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     1-31       5.89  357.78  0.00094       17.5%     43.26
  WD 2:  Seg  5    55-98       4.87  315.70  0.00346       15.0%     46.73
  WD 3:  Seg 11   133-179      5.85  356.48  0.00098       25.0%     49.30
  WD 4:  Seg 16   192-230      6.27  373.58  0.00057       25.0%     38.37
  WD 5:  Seg 20   250-287      6.73  392.62  0.00032       27.5%     41.69
  WD 6:  Seg 24   302-345      5.50  341.69  0.00155       10.0%     43.72
  WD 7:  Seg 27   349-387      4.59  304.36  0.00492        7.5%     25.09

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    1-31     -----------------Q--KTD----IISTVEFNH--TGELLATGDKGGRVVIFQ
   WD 2   55-98     HEPEFDY--------LKSLEIEE----KINKIRWLPQQNAAYFLLSTNDKTVKLWK
   WD 3  133-179    RPMDLMVEATPRRVFANA--HTY----HINSISVNS--DYETYMS-ADDLRINLWN
   WD 4  192-230    IKP--AN--------MEE--LTE----VITAAEFHP-HHCNTFVYSSSKGTIRLCD
   WD 5  250-287    -PSNRSF--------FSE--IIS----SISDVKFSH--SGRYIMTRD-YLTVKVWD
   WD 6  302-345    DYLRSKL--------CSL--YENDCIFDKFECVWNG--SDSVIMTGSYNNFFRMFD
   WD 7  349-387    -KRDVTL--------EAS--REN----SKPRAILKP--RKVCVGGKRRKDEISVDS

   WD40 Template    TGECLRT--------LSG--HTS----GVTSVSFSP--DGKRLVSGSEDGTIKVWD