Accession: ENSP00000354878 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000354878 (Len=1674)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000354878, Len=1674):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGY 80  
WD40-rpts                                                                                      

Query       81 NATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLF 160 
WD40-rpts                                                                                      

Query      161 DTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240 
WD40-rpts                                                                                      

Query      241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 480 
WD40-rpts                                                                                      

Query      481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKRLQ 560 
WD40-rpts                                                                                      

Query      561 KLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEK 640 
WD40-rpts                                                                                      

Query      641 ANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSE 720 
WD40-rpts                                                                                      

Query      721 YEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKK 800 
WD40-rpts                                                                                      

Query      801 DQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQ 880 
WD40-rpts                                                                                      

Query      881 KMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKR 960 
WD40-rpts                                                                                      

Query      961 REKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYL 1040
WD40-rpts                                                                                      

Query     1041 LDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDST 1120
WD40-rpts                                                                                      

Query     1121 DEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTE 1200
WD40-rpts                                                                                      

Query     1201 TSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRP 1280
WD40-rpts                                                                                      

Query     1281 RNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLL 1360
WD40-rpts                                                                                      

Query     1361 FTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSAS 1440
WD40-rpts        (_______________________WD 1_______________________)                          

Query     1441 TSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIK 1520
WD40-rpts                                   (________________________WD 2______________________

Query     1521 MFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLL 1600
WD40-rpts      __)(____________________WD 3____________________)       (_______________WD 4____

Query     1601 SGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1674
WD40-rpts      ___________)   (________________WD 5_______________)

5 WD40-repeats found in QUERY=ENSP00000354878 (Len=1674):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 13  1363-1414     3.11  243.02  0.03256       35.0%     37.01
  WD 2:  Seg 20  1470-1523     3.61  263.67  0.01728       32.5%     44.70
  WD 3:  Seg 24  1524-1569     3.75  269.60  0.01440       32.5%     24.39
  WD 4:  Seg 26  1577-1612     3.06  240.89  0.03475       25.0%     31.30
  WD 5:  Seg 28  1616-1652     3.32  251.69  0.02497       15.0%     31.26

Multiple sequence alignment of 5 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1363-1414   -GSKDR-----------TCKVWNLVTGQEIMSLGG--------HPNNV--VSVKY---CNYTSLVFTVS-TSYIKVWD
   WD 2 1470-1523   SGNAVRMWDLKRFQSTGKLT--------------G--------HLGPV--MCLTVDQISSGQDLIITGSKDHYIKMFD
   WD 3 1524-1569   VTEGAL-----------GTV--------------SPTHNFEPPHYDGI--EALTI---Q--GDNLFSGSRDNGIKKWD
   WD 4 1577-1612   ----QQ-----------VPN--------------A--------HKD--WVCALGV---VPDHPVLLSGCRGGILKVWN
   WD 5 1616-1652   -FMPVG-----------EMK--------------G--------HDSPI--NAICV-----NSTHIFTAADDRTVRIWK

   WD40 Template    TGECLR-----------TLS--------------G--------HTSGV--TSVSF---SPDGKRLVSGSEDGTIKVWD