Accession: ENSP00000349205 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000349205 (Len=1358)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000349205, Len=1358):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLNS 80  
WD40-rpts                                                                                      

Query       81 AQNCLPFQKASEKASEKAAMLFRQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWN 160 
WD40-rpts                                                                                      

Query      161 WVLLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRTRGELKRAMD 240 
WD40-rpts                                                                                      

Query      241 IFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIEDHSIRELVTQMIHREPDKRLEAEDYLKQQRGNAFPEIF 320 
WD40-rpts                                                                                      

Query      321 YTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGHDLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALE 400 
WD40-rpts                                                                                      

Query      401 LILHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRL 480 
WD40-rpts                                                                                      

Query      481 AYAENIALLAETALRFLELVQLKNLNMENDPNNEEIDEVTHPNGNYDTELQALHEMVQQKVVTLLSDPENIVKQTLMENG 560 
WD40-rpts                                                                                      

Query      561 ITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDSIVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALYALT 640 
WD40-rpts                                                                                      

Query      641 CMCQLGLLQKPHVYEFASDIAPFLCHPNLWIRYGAVGFITVVARQISTADVYCKLMPYLDPYITQPIIQIERKLVLLSVL 720 
WD40-rpts                                                                                      

Query      721 KEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMTEEEEDKLLALKDFMMKSNKA 800 
WD40-rpts                                                                                      

Query      801 KANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEPDDKRARKHVKQDSNVNEEWKSMFGSLDPPNMPQALPKGSD 880 
WD40-rpts                                                                                      

Query      881 QEVIQTGKPPRSESSAGICVPLSTSSQVPEVTTVQNKKPVIPVLSSTILPSTYQIRITTCKTELQQLIQQKREQCNAERI 960 
WD40-rpts                                                                                      

Query      961 AKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIWNSQKMEGKTTTTRSILTYSR 1040
WD40-rpts                            (_________________WD 1________________)          (________

Query     1041 IGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGS 1120
WD40-rpts      _________WD 2________________)   (_______________________WD 3___________________

Query     1121 LVGWDLRSSSNAWTLKHDLKSGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWV 1200
WD40-rpts      ____)   (__________________WD 4_________________)(____________________WD 5______

Query     1201 IAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAGSDMKIRFWDLAYPERSYVVA 1280
WD40-rpts      _____________)              (__________________WD 6_________________)           

Query     1281 GSTSSPSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRRGPESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK 1358
WD40-rpts                   (______________________________WD 7_____________________________)

7 WD40-repeats found in QUERY=ENSP00000349205 (Len=1358):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 13   983-1021     7.54  426.31  0.00011       30.0%     51.64
  WD 2:  Seg 17  1032-1070     7.11  408.24  0.00020       17.5%     54.93
  WD 3:  Seg 21  1074-1125     5.06  323.85  0.00269       17.5%     44.02
  WD 4:  Seg 25  1129-1169     5.98  361.74  0.00083       25.0%     54.01
  WD 5:  Seg 29  1170-1214     4.77  311.89  0.00389       10.0%     50.13
  WD 6:  Seg 34  1229-1269     6.02  363.33  0.00079       25.0%     45.08
  WD 7:  Seg 39  1294-1358     4.94  318.70  0.00315       32.5%     43.87

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  983-1021   -G---LLVAHLH------------------------E--HKSAVNRIR-VSD--EH-------------SL--FATCSNDGTVKIWN
   WD 2 1032-1070   -T---RSILTYS------------------------R--IGGRVKTLT-FCQ--GS-------------HY--LAIASDNGAVQLLG
   WD 3 1074-1125   -S---KLPKSPK------------------------I--HPLQSRILD-QKE--DGCVVDMHHFNSGAQSV--LAYATVNGSLVGWD
   WD 4 1129-1169   -S---SNAWTLK------------------------HDLKSGLITSFA-VDI--HQ-------------CW--LCIGTSSGTMACWD
   WD 5 1170-1214   MRFQLPISSHCH------------------------P--SRARIRRLS-MHP--LY-------------QSWVIAAVQGNNEVSMWD
   WD 6 1229-1269   -A---PPLSELQ------------------------P--SPHSVHGIY-CSPADGN-------------PI--LLTAGSDMKIRFWD
   WD 7 1294-1358   II---EGTEVVQEIQNKQKVGPSDDTPRRGPESLPVG--HHDIITDVATFQT--TQ-------------GF--IVTASRDGIVKVWK

   WD40 Template    TG---ECLRTLS------------------------G--HTSGVTSVS-FSP--DG-------------KR--LVSGSEDGTIKVWD