Accession: ENSP00000325074 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000325074 (Len=457)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000325074, Len=457):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MFPKFSLRSMFHGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGE 80  
WD40-rpts                                 (_________________WD 1________________)              

Query       81 YNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVT 160 
WD40-rpts             (____________________WD 2____________________)                           

Query      161 TLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT 240 
WD40-rpts                     (_________________WD 3________________)            (_____________

Query      241 AAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKI 320 
WD40-rpts      ____WD 4________________)                   (________________WD 5_______________

Query      321 WDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRT 400 
WD40-rpts      _)              (___________________WD 6___________________)  (_________________

Query      401 VLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN 457 
WD40-rpts      WD 7________________)

7 WD40-repeats found in QUERY=ENSP00000325074 (Len=457):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  3    28-66       7.61  429.17  0.00010       17.5%     37.98
  WD 2:  Seg  7    88-133      4.05  282.08  0.00980       15.0%     51.46
  WD 3:  Seg 14   176-214      7.54  426.05  0.00011       22.5%     46.67
  WD 4:  Seg 19   227-265      6.32  375.62  0.00054       25.0%     38.36
  WD 5:  Seg 22   285-322      6.41  379.56  0.00048       22.5%     41.54
  WD 6:  Seg 26   337-380      5.29  333.34  0.00200       10.0%     41.51
  WD 7:  Seg 29   383-421      5.07  323.90  0.00268       15.0%     23.55

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   28-66     KG-----AVDDDVAEAD----IISTVEFNH--SGELLATGDKGGRVVIFQ
   WD 2   88-133    QSHEPEFDYLKSLEIEE----KINKIRWLPQKNAAQFLLSTNDKTIKLWK
   WD 3  176-214    ASP----RRIFANAHTY----HINSISINS--DYETYLS-ADDLRINLWH
   WD 4  227-265    IKP------ANMEELTE----VITAAEFHP-NSCNTFVYSSSKGTIRLCD
   WD 5  285-322    -PS----NRSFFSEIIS----SISDVKFSH--SGRYMMTRD-YLSVKIWD
   WD 6  337-380    EYL----RSKLCSLYENDCIFDKFECCWNG--SDSVVMTGSYNNFFRMFD
   WD 7  383-421    -TK----RDITLEASRE----NNKPRTVLK--PRKVCASGKRKKDEISVD

   WD40 Template    TGE----CLRTLSGHTS----GVTSVSFSP--DGKRLVSGSEDGTIKVWD