Accession: ENSP00000308450 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000308450 (Len=499)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000308450, Len=499):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYI 80  
WD40-rpts                                                                                      

Query       81 PHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGS 160 
WD40-rpts                                                                                      

Query      161 SRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY 240 
WD40-rpts                  (________________WD 1________________)(___________________WD 2______

Query      241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPD 320 
WD40-rpts      _____________)   (________________WD 3_______________)    (_________________WD 4

Query      321 GRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHS 400 
WD40-rpts      ________________)       (__________________WD 5__________________)   (__________

Query      401 QVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARR 480 
WD40-rpts      _______WD 6_________________)   (_________________WD 7________________)         

Query      481 REREKASAAKSSLIHQGIR 499 
WD40-rpts

7 WD40-repeats found in QUERY=ENSP00000308450 (Len=499):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  4   173-210      4.56  302.85  0.00515       12.5%     45.78
  WD 2:  Seg  8   211-254      7.60  428.53  0.00010       20.0%     58.07
  WD 3:  Seg 12   258-294      6.70  391.56  0.00033       32.5%     53.49
  WD 4:  Seg 16   299-337      9.53  508.45  8.7e-06       37.5%     49.64
  WD 5:  Seg 20   345-386      6.21  371.35  0.00062       25.0%     45.07
  WD 6:  Seg 24   390-429      6.06  364.88  0.00075       35.0%     52.95
  WD 7:  Seg 28   433-471      9.65  513.35  7.5e-06       37.5%     54.76

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  173-210    -DR----ILDAPEIRNDYYLNLVDWSSGNVLAV---AL---DNSVYLWS
   WD 2  211-254    ASSGDILQLLQMEQPGEYISSVAWIKEGNYLAV---GTS--SAEVQLWD
   WD 3  258-294    -QK----RLRNMTSHSARVGSLSW--NSYILSS---GSR--SGHIHHHD
   WD 4  299-337    -EH----HVATLSGHSQEVCGLRWAPDGRHLAS---GGN--DNLVNVWP
   WD 5  345-386    -WV----PLQTFTQHQGAVKAVAWCPWQSNVLATGGGTS--DRHIRIWN
   WD 6  390-429    -GA----CLSAVDAH-SQVCSILWSPHYKELIS---GHGFAQNQLVIWK
   WD 7  433-471    -MA----KVAELKGHTSRVLSLTMSPDGATVAS---AAA--DETLRLWR

   WD40 Template    TGE----CLRTLSGHTSGVTSVSFSPDGKRLVS---GSE--DGTIKVWD