Accession: ENSP00000303191 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000303191 (Len=505)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000303191, Len=505):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSKENLKEKGPQNATDSYVHK 80  
WD40-rpts                                                                                      

Query       81 QYPANQGQEVEYFVAGVALTADTKIQRMPSESAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMET 160 
WD40-rpts                                                                     (________________

Query      161 GNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTV 240 
WD40-rpts      _WD 1________________)  (_________________WD 2________________)   (_____________

Query      241 RGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGH 320 
WD40-rpts      ____WD 3________________)   (_________________WD 4________________)   (_________

Query      321 TNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNL 400 
WD40-rpts      ________WD 5________________)   (________________WD 6________________)   (______

Query      401 SGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVY 480 
WD40-rpts      __________WD 7________________)           (_________________WD 8________________

Query      481 REDDTATEETHPVSWKPEIIKRKRF 505 
WD40-rpts      )

8 WD40-repeats found in QUERY=ENSP00000303191 (Len=505):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  2   144-182      5.01  321.60  0.00288        7.5%     19.41
  WD 2:  Seg  4   185-223      9.39  502.50  1.0e-05       37.5%     54.25
  WD 3:  Seg  8   227-265      9.68  514.70  7.2e-06       37.5%     56.02
  WD 4:  Seg 12   269-307      9.68  514.35  7.3e-06       32.5%     54.54
  WD 5:  Seg 16   311-349     10.19  535.56  3.8e-06       37.5%     54.53
  WD 6:  Seg 20   353-390      8.13  450.42  5.3e-05       35.0%     53.30
  WD 7:  Seg 24   394-431      8.82  479.18  2.2e-05       37.5%     51.51
  WD 8:  Seg 29   443-481      8.03  446.20  6.0e-05       25.0%     37.15

Multiple sequence alignment of 8 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  144-182    ASDRPQPTAMNSIVMETGNTKNSALMAKKAPTMPKPQWH
   WD 2  185-223    WKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWD
   WD 3  227-265    GKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWD
   WD 4  269-307    NKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWD
   WD 5  311-349    KASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWD
   WD 6  353-390    GKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWK
   WD 7  394-431    GSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGTMHLWD
   WD 8  443-481    AAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR

   WD40 Template    GECLRTLSGHTSGVTSVSFSPDGKRLVSGSEDGTIKVWD