Accession: ENSMUSP00000119004 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000119004 (Len=457)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000119004, Len=457):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 XARSVAGAGGGGCPAGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGE 80  
WD40-rpts                                 (_________________WD 1________________)              

Query       81 YNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRIT 160 
WD40-rpts                     (________________WD 2________________)                           

Query      161 ALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT 240 
WD40-rpts                     (_________________WD 3________________)            (_____________

Query      241 AAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKV 320 
WD40-rpts      ____WD 4________________)                   (________________WD 5_______________

Query      321 WDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRA 400 
WD40-rpts      _)              (___________________WD 6___________________)(__________________W

Query      401 SLKPRKVCTGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN 457 
WD40-rpts      D 7_________________)

7 WD40-repeats found in QUERY=ENSMUSP00000119004 (Len=457):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  2    28-66       7.42  421.18  0.00013       17.5%     40.38
  WD 2:  Seg  6    96-133      4.29  291.93  0.00722       17.5%     43.14
  WD 3:  Seg 11   176-214      7.81  437.17  8.0e-05       22.5%     50.26
  WD 4:  Seg 16   227-265      6.11  366.95  0.00071       25.0%     38.27
  WD 5:  Seg 20   285-322      6.64  389.02  0.00036       25.0%     41.75
  WD 6:  Seg 24   337-380      5.27  332.32  0.00207       10.0%     41.31
  WD 7:  Seg 27   381-421      5.45  339.64  0.00165       12.5%      5.72

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   28-66     KG-AVD-EDVAEAD----IISTVEFNY--SGDLLATGDKGGRVVIFQ
   WD 2   96-133    YLKSL-----EIEE----KINKIRWLPQQNAAHFLLSTNDKTIKLWK
   WD 3  176-214    ASPRRI-FANAHTY----HINSISVNS--DHETYLS-ADDLRINLWH
   WD 4  227-265    IKP--A-NMEELTE----VITAAEFHP-HQCNVFVYSSSKGTIRLCD
   WD 5  285-322    -PSSRS-FFSEIIS----SISDVKFSH--SGRYMMTRD-YLSVKVWD
   WD 6  337-380    EYLRSK-LCSLYENDCIFDKFECCWNG--SDSAIMTGSYNNFFRMFD
   WD 7  381-421    RNTRRDVTLEASRE----NSKPRASLK--PRKVCTGGKRKKDEISVD

   WD40 Template    TGECLR-TLSGHTS----GVTSVSFSP--DGKRLVSGSEDGTIKVWD