Accession: ENSMUSP00000118061 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000118061 (Len=2032)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000118061, Len=2032):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 XPLELRRLLRPPPGLDSESSGNESQKARHAGAVIRALSGMARHRGPARALRYFDLTPSMAGIMVPPVQRWPGAGFTFHAW 80  
WD40-rpts                                                                                      

Query       81 LCLQSSEAVPTSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHVPGR 160 
WD40-rpts                                                                                      

Query      161 RPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGSAGHRTTTTTTGLPASSVSTALAHTHPSLTRSQSVPASTGLGW 240 
WD40-rpts                                                                                      

Query      241 GPGLGTPLQEGSVSSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQPSALRVLCSLGPNEPAPFKPEGELHEFGTKLLLH 320 
WD40-rpts                                                                                      

Query      321 YSPQACKNNICLDLSPGHGLDGRLTGHRVETWDVKDVVNCVGGMGVLLPLLERVAVQPQEAEAGPCETHDLVGPELTSGR 400 
WD40-rpts                                                                                      

Query      401 NTQGLLLPLGKSSEDRMERNAVAAFLLMLRNFLQNHTVNQESLVQCQGPAIIGALLRKVPSSAMDMNVLMSAQLLMEQAA 480 
WD40-rpts                                                                                      

Query      481 ADGGGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSMVREHRQKLRKKYGVQFLLDALRTHYSPQRERPLAADDLRT 560 
WD40-rpts                                                                                      

Query      561 VQTSLLGLVREFLVRNFSVEDMQVVLNFLAATGDDGQILRRLQQNERLPERNRQRIRLHDCGLQGLVASLSEESISPQLC 640 
WD40-rpts                                                                                      

Query      641 QGLYKLFVGTGSGNTAGGGSSNGTVTPASQPGTPSPLDGPRPFPTAQGRHSSSLSNVLEDGSLLEPNISGDDTSNTSNPQ 720 
WD40-rpts                                                                                      

Query      721 QTPEEELCNLLTNVLFSVTWRGVEGSAEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPPGG 800 
WD40-rpts                                                                                      

Query      801 LANLSQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCNLLDRLGAWPHLANSTADLREMAQIGLRLVLGYILLEDPQL 880 
WD40-rpts                                                                                      

Query      881 HAQAYVKLHTLLQTAVPTRREEACYVLSKLEAALSRALTTSSSETEHASTAVAASERCSWLVPLVRTLLDRAYGPLGLQW 960 
WD40-rpts                                                                                      

Query      961 GLPSLPPTNGSPTFFEDFQAFCATAEWRHFIDKQVQPTMSKFEMDTYAKSHDLMSGFWNACYDTLMSSGQRHQRDRIQSR 1040
WD40-rpts                                                                                      

Query     1041 RAFKELVLEPAQRRARVEGLRYASVLKQQAAQHSTALLHWGALWRQLSSPCGAWALRIPPAPHWKLSSAETYSRMRLKLV 1120
WD40-rpts                                                                                      

Query     1121 PNHHFDPHLEASALRDNLGEAPMTPTEETSLPLAVTKEAKISAPPEELPEEQLGEEDLAALESLMEEAAELDEKREKLVL 1200
WD40-rpts                                                                                      

Query     1201 SAECQLVTVVAVVPGLLEITTQHVYFYDGSTERVETEEGIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNF 1280
WD40-rpts                                                                                      

Query     1281 PHKVAASSASSPCQAPRPQLYPIPSHTQLRNQVYSLLLRLRPPTQGYLSSRSPLEMLRASGLTQKWVQREISNFEYLMQL 1360
WD40-rpts                                                                                      

Query     1361 NTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSN 1440
WD40-rpts                                                                                      

Query     1441 AAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNE 1520
WD40-rpts                                                                                      

Query     1521 KVGDVVLPPWAGSPEDFIQKHRQALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKA 1600
WD40-rpts                                                                                      

Query     1601 LEGIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQNLNQLKAFFAEVVSEAVPLVLALVPHRQSHSFITQ 1680
WD40-rpts                                                                                      

Query     1681 SSSDMLVTVSASGLLGTHTWLPYDRNINNYFTFSKDPTMGSPKVQKLLSGPWVSDSGVSAQALAVAPDGKLLFSGGHWDG 1760
WD40-rpts                                                                                      

Query     1761 SLRVTSLPRGRLLNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVWRLLQQSGLSAGLAPKPVQVLYGHVAAVSCVAIS 1840
WD40-rpts               (_________________WD 1________________)            (_________________WD

Query     1841 TELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLPGPISHLALGAEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRA 1920
WD40-rpts       2________________)                                                             

Query     1921 SVTLTEQPTALTVAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQPSEV 2000
WD40-rpts                                     (__________________WD 3__________________)       

Query     2001 RSSQFARRLWRSSRRISQVSSGETEYNPGEAR 2032
WD40-rpts

3 WD40-repeats found in QUERY=ENSMUSP00000118061 (Len=2032):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 26  1770-1808     6.77  394.36  0.00030       40.0%     56.24
  WD 2:  Seg 30  1821-1859     5.24  331.05  0.00215       35.0%     53.60
  WD 3:  Seg 42  1952-1993     3.89  275.52  0.01200       22.5%     45.23

Multiple sequence alignment of 3 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1770-1808   -GRL--LNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVWR
   WD 2 1821-1859   -PKP--VQVLYGHVAAVSCVAISTELDMAVSGSEDGTVIIHT
   WD 3 1952-1993   LNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVG

   WD40 Template    TGEC--LRTLSGHTSGVTSVSFSPDGKRLVSGSEDGTIKVWD