Accession: ENSMUSP00000116252 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000116252 (Len=446)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000116252, Len=446):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAARKGRSRTCETGEPMEAETCDPGTEGPSQVYLPGRGPPLSEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNR 80  
WD40-rpts                                                                                      

Query       81 TELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPSPSEGSDDDEEDEDEEDEEEQKPQLELAMVPHYGGINRVRVSWL 160 
WD40-rpts                                                                       (______________

Query      161 GEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARIKPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKNVH 240 
WD40-rpts      WD 1______________)                           (________________WD 2_____________

Query      241 LWTPTEGGSWNVDQRPFVGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRRE 320 
WD40-rpts      __)(_____________________WD 3____________________)       (_________________WD 4_

Query      321 PFLLSGGDDGALKVWDLRQFKSGSPVATFKQHMAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPESGETETDPGL 400 
WD40-rpts      _______________)      (_________________WD 5_________________)(_________________

Query      401 AALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV 446 
WD40-rpts      _WD 6_________________)

6 WD40-repeats found in QUERY=ENSMUSP00000116252 (Len=446):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  7   146-179      3.28  250.00  0.02630       27.5%     39.11
  WD 2:  Seg 12   207-243      5.66  348.34  0.00126       20.0%     49.10
  WD 3:  Seg 16   244-290      6.79  395.28  0.00029       35.0%     47.97
  WD 4:  Seg 19   298-336      8.53  467.02  3.2e-05       37.5%     52.55
  WD 5:  Seg 23   343-382      7.38  419.51  0.00014       32.5%     53.22
  WD 6:  Seg 27   383-423      3.89  275.27  0.01209       20.0%     11.47

Multiple sequence alignment of 6 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  146-179    --------------VPHYGGINRVRVSW-LGE-EPV-AGVWSEKGQVEVFA
   WD 2  207-243    ----------IFSFAGHMGEGFALDWSP-RVPGRLL-TG--DCQKNVHLWT
   WD 3  244-290    PTEGGSWNVDQRPFVGHTRSVEDLQWSPTEDT-VFA-SC--SADASIRIWD
   WD 4  298-336    -AC------MLTTATAHDGDVNVISWSR-REP-FLL-SG--GDDGALKVWD
   WD 5  343-382    -GS------PVATFKQHMAPVTSVEWHPQDSG-VFA-AS--GADNQITQWD
   WD 6  383-423    LAV------ERDPESGETETDPGLAALP-QQL-LFVHQG--ETDLKELHWH

   WD40 Template    TGE------CLRTLSGHTSGVTSVSFSP-DGK-RLV-SG--SEDGTIKVWD