Accession: ENSMUSP00000115466 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000115466 (Len=427)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000115466, Len=427):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MSSFGIGKTKEVIFSMEEGSVKMFLRGRPVPMLIPDELAPTYSLDTRSELPSSRLKLDWVYGYRGRDCRANLYLLPTGEV 80  
WD40-rpts         (_________________WD 1_________________)                                     

Query       81 VYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRVWDSVSLSTLHVLGLGVFDR 160 
WD40-rpts                  (__________________WD 2_________________)          (________________

Query      161 AVCCVAFSKSNGGNLLCAVDESNDHVLSVWDWAKESKVVDSKCSNEAVLVATFHPTDPSLLITCGKSHIYFWSLEGGSLS 240 
WD40-rpts      _____WD 3_____________________)   (_________________WD 4________________)      (

Query      241 KRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQEVQGAHDGGVFALCALRDGTLVSGGGRDRRVVL 320 
WD40-rpts      _________________WD 5_________________)(___________________WD 6_________________

Query      321 WGSDYSKVQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILLGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKL 400 
WD40-rpts      _)   (_________________WD 7________________)  (_________________WD 8____________

Query      401 VHLWSSETHQPVWSRSIEVAATGHRDP 427 
WD40-rpts      ____)

8 WD40-repeats found in QUERY=ENSMUSP00000115466 (Len=427):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     4-43       4.22  288.88  0.00794       12.5%      7.76
  WD 2:  Seg  8    93-133      7.29  415.65  0.00016       25.0%     38.80
  WD 3:  Seg 12   144-191      5.50  342.06  0.00153       27.5%     42.46
  WD 4:  Seg 16   195-233      7.60  428.75  0.00010       15.0%     59.17
  WD 5:  Seg 20   240-279      5.04  322.99  0.00276       25.0%     47.45
  WD 6:  Seg 24   280-322      7.48  423.67  0.00012       22.5%     53.74
  WD 7:  Seg 28   326-364      7.32  416.96  0.00015       12.5%     56.87
  WD 8:  Seg 32   367-405      7.98  444.50  6.4e-05       15.0%     54.66

Multiple sequence alignment of 8 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    4-43     FGI---G----KTKEVIFSME--EGSVKMFLRGR----PVPMLIPDELAPTYS
   WD 2   93-133    VEE--QR----QRHYLGHNDD--IKCLAVHPDMV----TIATGQVAGTTKEGK
   WD 3  144-191    SVS---LSTLHVLGLGVFDRA--VCCVAFSKSNGGNLLCAVDESNDHVLSVWD
   WD 4  195-233    -ES---K----VVDSKCSNEA--VLVATFHPTDP----SLLITCGKSHIYFWS
   WD 5  240-279    -SK---R----QGLFEKHEKPKYVLCVTFLEGGD-----VVTGDSGGNLYVWG
   WD 6  280-322    KGGNRIT----QEVQGAHDGG--VFALCALRDGT----LVSGGGRDRRVVLWG
   WD 7  326-364    -SK---V----QEVEVPEDFG--PVRTVAEGRGD----TLYVGTTRNSILLGS
   WD 8  367-405    -TG---F----SLLVQGHVEE--LWGLATHPSRA----QFVTCGQDKLVHLWS

   WD40 Template    TGE---C----LRTLSGHTSG--VTSVSFSPDGK----RLVSGSEDGTIKVWD