Accession: ENSMUSP00000085985 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000085985 (Len=1672)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000085985, Len=1672):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MLGAADESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGY 80  
WD40-rpts                                                                                      

Query       81 NATVFAYGQTGAGKTYTMGTGFDVNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLF 160 
WD40-rpts                                                                                      

Query      161 DTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240 
WD40-rpts                                                                                      

Query      241 PQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRARITQLVSEQANQVLARAGEGNEEISNMIH 480 
WD40-rpts                                                                                      

Query      481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSASSAFSPTILSSDKETIEIIDLAKKDLEKLKRKEKKKKKRLQ 560 
WD40-rpts                                                                                      

Query      561 KLEESGREERSVAGKDDNADTDQEKKEEKGVSEKENNELDVEENQEVSDHEDEEEEEEDEEEEDDIEGEESSDESDSESD 640 
WD40-rpts                                                                                      

Query      641 EKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVK 720 
WD40-rpts                                                                                      

Query      721 CEYEKKLHAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQL 800 
WD40-rpts                                                                                      

Query      801 KKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSESPAPDTGSSAASGEADTSRPGT 880 
WD40-rpts                                                                                      

Query      881 QQKMRIPVARVQALPTPTTNGTRKKYQRKGFTGRVFTSKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLRQREELT 960 
WD40-rpts                                                                                      

Query      961 KRREKLSKRREKIVKESGEGDKSVANIIEEMESLTANIDYINDSIADCQANIMQMEEAKEEGETLDVTAVINACTLTEAR 1040
WD40-rpts                                                                                      

Query     1041 YLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDGAPPENEED 1120
WD40-rpts                                                                                      

Query     1121 SSEEDGPLHSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSEVASDTSAGDASLSGPLAPVAEGQEIGMN 1200
WD40-rpts                                                                                      

Query     1201 TETSGTSARDKELLAPSGLPSKIGSISRQSSLSEKKVPEPSPVTRRKAYEKADKPKAKEHKHSDSGASETSLSPPSSPPS 1280
WD40-rpts                                                                                      

Query     1281 RPRNELNVFNRLTVPQGTPSVQQDKSDESDSSLSEVHRGIINPFPACKGVRASPLQCVHIAEGHTKAVLCVDSTDDLLFT 1360
WD40-rpts                                                                 (_____________WD 1___

Query     1361 GSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTS 1440
WD40-rpts      __________)        (______________WD 2_____________)                            

Query     1441 RTVAIPSGESQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMF 1520
WD40-rpts                                          (____________________WD 3___________________

Query     1521 DVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSG 1600
WD40-rpts      )(____________________WD 4____________________)    (_________________WD 5_______

Query     1601 CRGGILKLWNVDTFVPVGEMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDIASN 1672
WD40-rpts      _________)   (________________WD 6_______________)

6 WD40-repeats found in QUERY=ENSMUSP00000085985 (Len=1672):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 14  1340-1371     4.16  286.68  0.00850       37.5%     30.74
  WD 2:  Seg 17  1380-1412     3.04  240.04  0.03565       27.5%     42.47
  WD 3:  Seg 24  1477-1521     3.31  251.42  0.02518       27.5%     39.05
  WD 4:  Seg 27  1522-1567     3.73  268.59  0.01485       32.5%     25.84
  WD 5:  Seg 29  1572-1610     4.88  316.41  0.00338       25.0%     30.94
  WD 6:  Seg 31  1614-1650     2.98  237.75  0.03823       15.0%     33.38

Multiple sequence alignment of 6 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1340-1371   IAE--------G--------HTKAVLCVDS---TDD--LLFTGSKDRTCKVWN
   WD 2 1380-1412   --------SLGV--------HPNNVVSVKY---CNYTSLVFTVSTS-YIKVWD
   WD 3 1477-1521   LKRFQSTGKLTG--------HLGPVMCLTVDQISNGQDLIITGSKDHYIKMFD
   WD 4 1522-1567   VTE--GALGTVSPTHNFEPPHYDGIEALAI---Q--GDNLFSGSRDNGIKKWD
   WD 5 1572-1610   -GL--LQQVPNA--------HKDWVCALGL---VPGHPVLLSGCRGGILKLWN
   WD 6 1614-1650   -FV--PVGEMRG--------HDSPINAICV-----NSTHVFTAADDRTVRIWK

   WD40 Template    TGE--CLRTLSG--------HTSGVTSVSF---SPDGKRLVSGSEDGTIKVWD