Accession: ENSMUSP00000078703 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000078703 (Len=431)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000078703, Len=431):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGH 80  
WD40-rpts                                                           (__________________________

Query       81 TGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWN 160 
WD40-rpts      WD 1_________________________)          (_________________WD 2_________________)

Query      161 VGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVANNFEEPVALQEMDTSNGVLLPFYDPDSSI 240 
WD40-rpts         (_________________WD 3_________________)        (___________________WD 4_____

Query      241 VYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQD 320 
WD40-rpts      ______________)  (__________________WD 5_________________)  (___________________

Query      321 DLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPASPRRSQSASEAPLSQHTLETLLE 400 
WD40-rpts      _____WD 6_______________________)                                               

Query      401 EIKALRDRVQAQEERITALENMLCELVDGTD 431 
WD40-rpts

6 WD40-repeats found in QUERY=ENSMUSP00000078703 (Len=431):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  5    54-110      7.03  404.96  0.00022       30.0%     44.29
  WD 2:  Seg  9   121-160      7.44  422.13  0.00013       32.5%     40.03
  WD 3:  Seg 13   164-203      8.05  447.20  5.8e-05       30.0%     54.45
  WD 4:  Seg 18   212-255      5.74  351.72  0.00113       17.5%     49.40
  WD 5:  Seg 22   258-298      3.79  271.26  0.01368       12.5%     37.08
  WD 6:  Seg 26   301-353      4.39  296.19  0.00633       15.0%     25.49

Multiple sequence alignment of 6 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   54-110    GGGGAFIVLPLAKTGRVDKN--YPLVTG-HTGPVLDIDWCPHNDNV-I-AS-----------ASDDTTVMVWQ
   WD 2  121-160    -T----------------EP--VITLEG-HSKRVGILSWHP-TARNVL-LS-----------AGGDNVIIIWN
   WD 3  164-203    -G----------------EV--LLSLDDIHPDVIHSVCWNS-NGSL-L-AT-----------TCKDKTLRIID
   WD 4  212-255    NN-------------FEEPV--ALQEMD-TSNGVLLPFYDP-DSSI-VYLC-----------GKGDSSIRYFE
   WD 5  258-298    EE----------------PP-FVHYLNT-FSSKEPQRGMGF-MPKR-G-LD-----------VSKCEIARFYK
   WD 6  301-353    ER----------------KCEPIIMTVP-RKSDLFQDDLYP-DTPG-P-EPALEADEWLSGQDAEPVLISLKE

   WD40 Template    TG----------------EC--LRTLSG-HTSGVTSVSFSP-DGKR-L-VS-----------GSEDGTIKVWD