Accession: ENSMUSP00000074661 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000074661 (Len=1624)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000074661, Len=1624):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYN 80  
WD40-rpts                                                                                      

Query       81 ATVLAYGQTGAGKTYTMGTGFDTVTSEEEQGIIPRAIAHLFRGIDERKRRAQEKGVTGPEFKVSAQFLELYNEEILDLFD 160 
WD40-rpts                                                                                      

Query      161 STRDPDARHRRSNIKIHEDANGGIYTTGVTSRLINSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRVCA 240 
WD40-rpts                                                                                      

Query      241 QPDLVNETVTGLPDGAAPTGTEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKAGKRVIGEDGTEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQ 480 
WD40-rpts                                                                                      

Query      481 NYIREIEELRTKLLESEAMNESLRRSLSRASARNPYSLGASPAGPAFGGSPATSMEDASEVIRKAKQDLERLKKKEVRQR 560 
WD40-rpts                                                                                      

Query      561 RKSPEKEAFKKRAKLQAENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADL 640 
WD40-rpts                                                                                      

Query      641 TCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNR 720 
WD40-rpts                                                                                      

Query      721 DLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR 800 
WD40-rpts                                                                                      

Query      801 ALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGLKPPNMDSGAEVSASTTSSEAESGARSVSSIVRQWNRKIDH 880 
WD40-rpts                                                                                      

Query      881 FLGDRPTATVNGGRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRR 960 
WD40-rpts                                                                                      

Query      961 KREHLQAESPEEEKGLQELAEEIEVLAANIDYINDSITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLK 1040
WD40-rpts                                                                                      

Query     1041 ASIDKGLQVAQKEAQIRLLEGRLRQTDMTGSSQNHLLLDALREKAEAHPELQALIYNVQHENGYASTDEEVSEFSEGSFS 1120
WD40-rpts                                                                                      

Query     1121 QSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDSSTKNITKSLASLVEIKEDGVGFSIRDPYYRDKVSRTVSLP 1200
WD40-rpts                                                                                      

Query     1201 TRGSTFPRQSRGATDTSPLTRRKSYDRGQPIRSTDMGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSE 1280
WD40-rpts                                                                                      

Query     1281 VLRGIITPIGGAKGARTAPLQCISMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCS 1360
WD40-rpts                         (________________WD 1_______________)         (_____________W

Query     1361 HSGLVFSVSSSYIKVWDIRDSAKCIRTLTSSGQVISGDACIATSTRAITSAQGEHQINQMALSPSGSMLYVASGNAVRIW 1440
WD40-rpts      D 2_____________)                                                               

Query     1441 ELNRFQPIGKLTGHIGPVMCLTVTQTSNQHDLVVTGSKDHYVKMFQLGDCVTGTIGPTHNFEPPHYDGIECLAIQGDILF 1520
WD40-rpts       (____________________WD 3___________________)(____________________WD 4_________

Query     1521 SGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGFIKVWNVDNFTPIGEIKGHDSPINAICTNSK 1600
WD40-rpts      ___________)         (______________WD 5______________)   (________________WD 6_

Query     1601 HIFTASSDLTVKFWSIRRLPAAHP 1624
WD40-rpts      ______________)

6 WD40-repeats found in QUERY=ENSMUSP00000074661 (Len=1624):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 11  1300-1336     3.61  263.72  0.01726       25.0%     18.86
  WD 2:  Seg 13  1346-1377     3.80  271.59  0.01354       30.0%     40.30
  WD 3:  Seg 20  1442-1486     4.68  307.92  0.00440       25.0%     39.32
  WD 4:  Seg 23  1487-1532     4.16  286.57  0.00853       37.5%     24.21
  WD 5:  Seg 25  1542-1575     3.06  240.89  0.03474       25.0%     31.53
  WD 6:  Seg 27  1579-1615     3.18  245.89  0.02982       22.5%     29.94

Multiple sequence alignment of 6 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1300-1336   -LQC--ISMAEG--------HTKPI--LCLDA---T--DELLFTGSKDRSCKMWN
   WD 2 1346-1377   ---------LKG--------HPNNV--VSIKY---CSHSGLVFSVSSS-YIKVWD
   WD 3 1442-1486   LNRFQPIGKLTG--------HIGPV--MCLTVTQTSNQHDLVVTGSKDHYVKMFQ
   WD 4 1487-1532   LGDC--VTGTIGPTHNFEPPHYDGI--ECLAI---Q--GDILFSGSRDNGIKKWD
   WD 5 1542-1575   --------IPNA--------HKD--WVCALAF---VPGRPMLLSACRAGFIKVWN
   WD 6 1579-1615   -FTP--IGEIKG--------HDSPI--NAIC-----TNSKHIFTASSDLTVKFWS

   WD40 Template    TGEC--LRTLSG--------HTSGV--TSVSF---SPDGKRLVSGSEDGTIKVWD