co-expression network

GO Enrichment Analysis of Co-expressed Genes with

AT3G50910

GO-BP

GO-MF

GO-CC

Rank	GO Term	Adjusted P value
1	GO:0043462: regulation of ATPase activity	0.00E+00
2	GO:0009991: response to extracellular stimulus	0.00E+00
3	GO:0080169: cellular response to boron-containing substance deprivation	0.00E+00
4	GO:0032780: negative regulation of ATPase activity	0.00E+00
5	GO:0036258: multivesicular body assembly	0.00E+00
6	GO:0048227: plasma membrane to endosome transport	0.00E+00
7	GO:0007205: protein kinase C-activating G-protein coupled receptor signaling pathway	1.57E-04
8	GO:0046167: glycerol-3-phosphate biosynthetic process	2.27E-04
9	GO:0006805: xenobiotic metabolic process	2.27E-04
10	GO:0000303: response to superoxide	2.27E-04
11	GO:0080173: male-female gamete recognition during double fertilization	2.27E-04
12	GO:0010726: positive regulation of hydrogen peroxide metabolic process	2.27E-04
13	GO:0009962: regulation of flavonoid biosynthetic process	2.27E-04
14	GO:0010265: SCF complex assembly	2.27E-04
15	GO:0034214: protein hexamerization	2.27E-04
16	GO:0010201: response to continuous far red light stimulus by the high-irradiance response system	2.27E-04
17	GO:0006098: pentose-phosphate shunt	3.00E-04
18	GO:0016310: phosphorylation	5.01E-04
19	GO:0031648: protein destabilization	5.05E-04
20	GO:0071395: cellular response to jasmonic acid stimulus	5.05E-04
21	GO:0006641: triglyceride metabolic process	5.05E-04
22	GO:0019521: D-gluconate metabolic process	5.05E-04
23	GO:0019374: galactolipid metabolic process	5.05E-04
24	GO:0030010: establishment of cell polarity	5.05E-04
25	GO:1902000: homogentisate catabolic process	5.05E-04
26	GO:0019441: tryptophan catabolic process to kynurenine	5.05E-04
27	GO:0097054: L-glutamate biosynthetic process	5.05E-04
28	GO:0046740: transport of virus in host, cell to cell	5.05E-04
29	GO:0006468: protein phosphorylation	5.98E-04
30	GO:0010043: response to zinc ion	6.34E-04
31	GO:0009867: jasmonic acid mediated signaling pathway	7.12E-04
32	GO:0009072: aromatic amino acid family metabolic process	8.21E-04
33	GO:0048586: regulation of long-day photoperiodism, flowering	8.21E-04
34	GO:0019563: glycerol catabolic process	8.21E-04
35	GO:0010359: regulation of anion channel activity	8.21E-04
36	GO:0007188: adenylate cyclase-modulating G-protein coupled receptor signaling pathway	8.21E-04
37	GO:0006556: S-adenosylmethionine biosynthetic process	8.21E-04
38	GO:0015031: protein transport	1.10E-03
39	GO:0010071: root meristem specification	1.17E-03
40	GO:0070301: cellular response to hydrogen peroxide	1.17E-03
41	GO:0006537: glutamate biosynthetic process	1.17E-03
42	GO:0006072: glycerol-3-phosphate metabolic process	1.17E-03
43	GO:0006809: nitric oxide biosynthetic process	1.17E-03
44	GO:0009399: nitrogen fixation	1.17E-03
45	GO:0070676: intralumenal vesicle formation	1.17E-03
46	GO:0001676: long-chain fatty acid metabolic process	1.17E-03
47	GO:0031348: negative regulation of defense response	1.27E-03
48	GO:0051603: proteolysis involved in cellular protein catabolic process	1.48E-03
49	GO:0009306: protein secretion	1.50E-03
50	GO:0019676: ammonia assimilation cycle	1.56E-03
51	GO:0010363: regulation of plant-type hypersensitive response	1.56E-03
52	GO:0042991: transcription factor import into nucleus	1.56E-03
53	GO:0031087: deadenylation-independent decapping of nuclear-transcribed mRNA	1.56E-03
54	GO:0010188: response to microbial phytotoxin	1.56E-03
55	GO:0006878: cellular copper ion homeostasis	1.56E-03
56	GO:0006542: glutamine biosynthetic process	1.56E-03
57	GO:0046686: response to cadmium ion	1.72E-03
58	GO:0046323: glucose import	1.89E-03
59	GO:0006891: intra-Golgi vesicle-mediated transport	2.33E-03
60	GO:0010193: response to ozone	2.33E-03
61	GO:0006979: response to oxidative stress	2.36E-03
62	GO:0006751: glutathione catabolic process	2.45E-03
63	GO:0070814: hydrogen sulfide biosynthetic process	2.45E-03
64	GO:0048317: seed morphogenesis	2.45E-03
65	GO:1902456: regulation of stomatal opening	2.45E-03
66	GO:0009117: nucleotide metabolic process	2.45E-03
67	GO:0006574: valine catabolic process	2.45E-03
68	GO:0035435: phosphate ion transmembrane transport	2.45E-03
69	GO:0045899: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.45E-03
70	GO:0010942: positive regulation of cell death	2.45E-03
71	GO:0006464: cellular protein modification process	2.82E-03
72	GO:0006886: intracellular protein transport	2.92E-03
73	GO:0010555: response to mannitol	2.94E-03
74	GO:2000067: regulation of root morphogenesis	2.94E-03
75	GO:0080060: integument development	2.94E-03
76	GO:0009094: L-phenylalanine biosynthetic process	2.94E-03
77	GO:0006904: vesicle docking involved in exocytosis	2.99E-03
78	GO:0009610: response to symbiotic fungus	3.47E-03
79	GO:0045995: regulation of embryonic development	3.47E-03
80	GO:0006955: immune response	3.47E-03
81	GO:0071446: cellular response to salicylic acid stimulus	3.47E-03
82	GO:0015937: coenzyme A biosynthetic process	3.47E-03
83	GO:0009816: defense response to bacterium, incompatible interaction	3.55E-03
84	GO:0006511: ubiquitin-dependent protein catabolic process	3.99E-03
85	GO:0006102: isocitrate metabolic process	4.02E-03
86	GO:0006644: phospholipid metabolic process	4.02E-03
87	GO:0010078: maintenance of root meristem identity	4.02E-03
88	GO:0010492: maintenance of shoot apical meristem identity	4.02E-03
89	GO:0009880: embryonic pattern specification	4.60E-03
90	GO:0006367: transcription initiation from RNA polymerase II promoter	4.60E-03
91	GO:0007186: G-protein coupled receptor signaling pathway	4.60E-03
92	GO:0030968: endoplasmic reticulum unfolded protein response	4.60E-03
93	GO:0048527: lateral root development	5.06E-03
94	GO:0007338: single fertilization	5.22E-03
95	GO:0046685: response to arsenic-containing substance	5.22E-03
96	GO:0009617: response to bacterium	5.54E-03
97	GO:0009873: ethylene-activated signaling pathway	5.66E-03
98	GO:0042761: very long-chain fatty acid biosynthetic process	5.85E-03
99	GO:2000280: regulation of root development	5.85E-03
100	GO:0016571: histone methylation	5.85E-03
101	GO:0048268: clathrin coat assembly	5.85E-03
102	GO:0008202: steroid metabolic process	5.85E-03
103	GO:0010629: negative regulation of gene expression	6.51E-03
104	GO:0000103: sulfate assimilation	6.51E-03
105	GO:0019538: protein metabolic process	6.51E-03
106	GO:0043069: negative regulation of programmed cell death	6.51E-03
107	GO:0006631: fatty acid metabolic process	6.58E-03
108	GO:0051707: response to other organism	7.14E-03
109	GO:0030148: sphingolipid biosynthetic process	7.20E-03
110	GO:0072593: reactive oxygen species metabolic process	7.20E-03
111	GO:0015770: sucrose transport	7.20E-03
112	GO:0009750: response to fructose	7.20E-03
113	GO:0048229: gametophyte development	7.20E-03
114	GO:0012501: programmed cell death	7.92E-03
115	GO:0006855: drug transmembrane transport	8.34E-03
116	GO:0010102: lateral root morphogenesis	8.66E-03
117	GO:0007049: cell cycle	8.87E-03
118	GO:0009651: response to salt stress	9.08E-03
119	GO:0009723: response to ethylene	9.28E-03
120	GO:0009887: animal organ morphogenesis	9.42E-03
121	GO:0007034: vacuolar transport	9.42E-03
122	GO:0002237: response to molecule of bacterial origin	9.42E-03
123	GO:0009736: cytokinin-activated signaling pathway	9.64E-03
124	GO:0009809: lignin biosynthetic process	9.64E-03
125	GO:0010053: root epidermal cell differentiation	1.02E-02
126	GO:0042343: indole glucosinolate metabolic process	1.02E-02
127	GO:0006952: defense response	1.06E-02
128	GO:0034976: response to endoplasmic reticulum stress	1.10E-02
129	GO:0046777: protein autophosphorylation	1.11E-02
130	GO:2000377: regulation of reactive oxygen species metabolic process	1.19E-02
131	GO:0016575: histone deacetylation	1.27E-02
132	GO:0045892: negative regulation of transcription, DNA-templated	1.30E-02
133	GO:0098542: defense response to other organism	1.36E-02
134	GO:0061077: chaperone-mediated protein folding	1.36E-02
135	GO:0010017: red or far-red light signaling pathway	1.45E-02
136	GO:0030433: ubiquitin-dependent ERAD pathway	1.45E-02
137	GO:0035428: hexose transmembrane transport	1.45E-02
138	GO:0006730: one-carbon metabolic process	1.45E-02
139	GO:0080092: regulation of pollen tube growth	1.45E-02
140	GO:0009693: ethylene biosynthetic process	1.54E-02
141	GO:0010087: phloem or xylem histogenesis	1.83E-02
142	GO:0010118: stomatal movement	1.83E-02
143	GO:0042631: cellular response to water deprivation	1.83E-02
144	GO:0080022: primary root development	1.83E-02
145	GO:0009845: seed germination	1.87E-02
146	GO:0055114: oxidation-reduction process	1.91E-02
147	GO:0071472: cellular response to salt stress	1.93E-02
148	GO:0010154: fruit development	1.93E-02
149	GO:0010197: polar nucleus fusion	1.93E-02
150	GO:0009790: embryo development	2.02E-02
151	GO:0042752: regulation of circadian rhythm	2.03E-02
152	GO:0048544: recognition of pollen	2.03E-02
153	GO:0055072: iron ion homeostasis	2.14E-02
154	GO:0010183: pollen tube guidance	2.14E-02
155	GO:0048825: cotyledon development	2.14E-02
156	GO:0009749: response to glucose	2.14E-02
157	GO:0048510: regulation of timing of transition from vegetative to reproductive phase	2.24E-02
158	GO:0071554: cell wall organization or biogenesis	2.24E-02
159	GO:0002229: defense response to oomycetes	2.24E-02
160	GO:0007264: small GTPase mediated signal transduction	2.35E-02
161	GO:0010583: response to cyclopentenone	2.35E-02
162	GO:0016032: viral process	2.35E-02
163	GO:0071281: cellular response to iron ion	2.46E-02
164	GO:0007275: multicellular organism development	2.55E-02
165	GO:0009734: auxin-activated signaling pathway	2.56E-02
166	GO:0009567: double fertilization forming a zygote and endosperm	2.57E-02
167	GO:0006470: protein dephosphorylation	2.73E-02
168	GO:0000910: cytokinesis	2.80E-02
169	GO:0010468: regulation of gene expression	2.85E-02
170	GO:0009911: positive regulation of flower development	2.91E-02
171	GO:0009788: negative regulation of abscisic acid-activated signaling pathway	3.03E-02
172	GO:0042128: nitrate assimilation	3.15E-02
173	GO:0048573: photoperiodism, flowering	3.27E-02
174	GO:0006888: ER to Golgi vesicle-mediated transport	3.27E-02
175	GO:0006950: response to stress	3.27E-02
176	GO:0009738: abscisic acid-activated signaling pathway	3.28E-02
177	GO:0009817: defense response to fungus, incompatible interaction	3.52E-02
178	GO:0035556: intracellular signal transduction	3.65E-02
179	GO:0010311: lateral root formation	3.65E-02
180	GO:0006499: N-terminal protein myristoylation	3.77E-02
181	GO:0009407: toxin catabolic process	3.77E-02
182	GO:0007568: aging	3.90E-02
183	GO:0009910: negative regulation of flower development	3.90E-02
184	GO:0010119: regulation of stomatal movement	3.90E-02
185	GO:0006970: response to osmotic stress	3.96E-02
186	GO:0009860: pollen tube growth	3.96E-02
187	GO:0006099: tricarboxylic acid cycle	4.30E-02
188	GO:0048366: leaf development	4.33E-02
189	GO:0080167: response to karrikin	4.56E-02
190	GO:0006897: endocytosis	4.71E-02
191	GO:0007169: transmembrane receptor protein tyrosine kinase signaling pathway	4.71E-02
192	GO:0010200: response to chitin	4.71E-02
193	GO:0042542: response to hydrogen peroxide	4.85E-02
194	GO:0044550: secondary metabolite biosynthetic process	4.94E-02
195	GO:0009744: response to sucrose	4.98E-02

Rank	GO Term	Adjusted P value
1	GO:0005365: myo-inositol transmembrane transporter activity	0.00E+00
2	GO:0016034: maleylacetoacetate isomerase activity	0.00E+00
3	GO:0015576: sorbitol transmembrane transporter activity	0.00E+00
4	GO:0004622: lysophospholipase activity	0.00E+00
5	GO:0015930: glutamate synthase activity	0.00E+00
6	GO:0033550: MAP kinase tyrosine phosphatase activity	0.00E+00
7	GO:0015591: D-ribose transmembrane transporter activity	0.00E+00
8	GO:0015148: D-xylose transmembrane transporter activity	0.00E+00
9	GO:0004370: glycerol kinase activity	0.00E+00
10	GO:0015575: mannitol transmembrane transporter activity	0.00E+00
11	GO:0003846: 2-acylglycerol O-acyltransferase activity	0.00E+00
12	GO:0042030: ATPase inhibitor activity	0.00E+00
13	GO:0005524: ATP binding	1.37E-08
14	GO:0004713: protein tyrosine kinase activity	1.44E-05
15	GO:0005515: protein binding	2.88E-05
16	GO:0015145: monosaccharide transmembrane transporter activity	5.85E-05
17	GO:0008565: protein transporter activity	8.85E-05
18	GO:0008113: peptide-methionine (S)-S-oxide reductase activity	1.19E-04
19	GO:0004616: phosphogluconate dehydrogenase (decarboxylating) activity	1.19E-04
20	GO:0102391: decanoate--CoA ligase activity	1.19E-04
21	GO:0004143: diacylglycerol kinase activity	1.57E-04
22	GO:0004467: long-chain fatty acid-CoA ligase activity	1.57E-04
23	GO:0090430: caffeoyl-CoA: alcohol caffeoyl transferase activity	2.27E-04
24	GO:0015168: glycerol transmembrane transporter activity	2.27E-04
25	GO:0016041: glutamate synthase (ferredoxin) activity	2.27E-04
26	GO:0003951: NAD+ kinase activity	2.48E-04
27	GO:0004674: protein serine/threonine kinase activity	3.99E-04
28	GO:0004594: pantothenate kinase activity	5.05E-04
29	GO:0045140: inositol phosphoceramide synthase activity	5.05E-04
30	GO:0032934: sterol binding	5.05E-04
31	GO:0004061: arylformamidase activity	5.05E-04
32	GO:0019200: carbohydrate kinase activity	5.05E-04
33	GO:0004450: isocitrate dehydrogenase (NADP+) activity	5.05E-04
34	GO:0004385: guanylate kinase activity	5.05E-04
35	GO:0008517: folic acid transporter activity	5.05E-04
36	GO:0004566: beta-glucuronidase activity	5.05E-04
37	GO:0004478: methionine adenosyltransferase activity	8.21E-04
38	GO:0001664: G-protein coupled receptor binding	8.21E-04
39	GO:0005093: Rab GDP-dissociation inhibitor activity	8.21E-04
40	GO:0008442: 3-hydroxyisobutyrate dehydrogenase activity	8.21E-04
41	GO:0003840: gamma-glutamyltransferase activity	8.21E-04
42	GO:0036374: glutathione hydrolase activity	8.21E-04
43	GO:0031683: G-protein beta/gamma-subunit complex binding	8.21E-04
44	GO:0004781: sulfate adenylyltransferase (ATP) activity	8.21E-04
45	GO:0016805: dipeptidase activity	8.21E-04
46	GO:0005354: galactose transmembrane transporter activity	1.17E-03
47	GO:0016756: glutathione gamma-glutamylcysteinyltransferase activity	1.17E-03
48	GO:0004298: threonine-type endopeptidase activity	1.17E-03
49	GO:0016301: kinase activity	1.28E-03
50	GO:0047769: arogenate dehydratase activity	1.56E-03
51	GO:0004664: prephenate dehydratase activity	1.56E-03
52	GO:0004301: epoxide hydrolase activity	1.56E-03
53	GO:0016887: ATPase activity	1.83E-03
54	GO:0030276: clathrin binding	1.89E-03
55	GO:0004356: glutamate-ammonia ligase activity	1.99E-03
56	GO:0051538: 3 iron, 4 sulfur cluster binding	1.99E-03
57	GO:0005355: glucose transmembrane transporter activity	2.03E-03
58	GO:0031593: polyubiquitin binding	2.45E-03
59	GO:0047714: galactolipase activity	2.45E-03
60	GO:0036402: proteasome-activating ATPase activity	2.45E-03
61	GO:0003950: NAD+ ADP-ribosyltransferase activity	2.94E-03
62	GO:0008506: sucrose:proton symporter activity	3.47E-03
63	GO:0008235: metalloexopeptidase activity	3.47E-03
64	GO:0102425: myricetin 3-O-glucosyltransferase activity	3.47E-03
65	GO:0102360: daphnetin 3-O-glucosyltransferase activity	3.47E-03
66	GO:0004620: phospholipase activity	3.47E-03
67	GO:0030246: carbohydrate binding	3.92E-03
68	GO:0035064: methylated histone binding	4.02E-03
69	GO:0047893: flavonol 3-O-glucosyltransferase activity	4.02E-03
70	GO:0052747: sinapyl alcohol dehydrogenase activity	4.02E-03
71	GO:0004869: cysteine-type endopeptidase inhibitor activity	4.02E-03
72	GO:0008142: oxysterol binding	4.60E-03
73	GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific)	4.60E-03
74	GO:0008970: phosphatidylcholine 1-acylhydrolase activity	4.60E-03
75	GO:0004672: protein kinase activity	4.95E-03
76	GO:0071949: FAD binding	5.22E-03
77	GO:0045309: protein phosphorylated amino acid binding	5.85E-03
78	GO:0047617: acyl-CoA hydrolase activity	5.85E-03
79	GO:0004712: protein serine/threonine/tyrosine kinase activity	6.05E-03
80	GO:0005545: 1-phosphatidylinositol binding	6.51E-03
81	GO:0004177: aminopeptidase activity	7.20E-03
82	GO:0008559: xenobiotic-transporting ATPase activity	7.20E-03
83	GO:0019904: protein domain specific binding	7.20E-03
84	GO:0045551: cinnamyl-alcohol dehydrogenase activity	7.92E-03
85	GO:0031072: heat shock protein binding	8.66E-03
86	GO:0051287: NAD binding	8.66E-03
87	GO:0005315: inorganic phosphate transmembrane transporter activity	8.66E-03
88	GO:0017025: TBP-class protein binding	1.02E-02
89	GO:0016787: hydrolase activity	1.03E-02
90	GO:0004725: protein tyrosine phosphatase activity	1.10E-02
91	GO:0003954: NADH dehydrogenase activity	1.19E-02
92	GO:0004407: histone deacetylase activity	1.19E-02
93	GO:0043130: ubiquitin binding	1.19E-02
94	GO:0005528: FK506 binding	1.19E-02
95	GO:0043424: protein histidine kinase binding	1.27E-02
96	GO:0004871: signal transducer activity	1.35E-02
97	GO:0042803: protein homodimerization activity	1.35E-02
98	GO:0035251: UDP-glucosyltransferase activity	1.36E-02
99	GO:0022891: substrate-specific transmembrane transporter activity	1.54E-02
100	GO:0003924: GTPase activity	1.66E-02
101	GO:0047134: protein-disulfide reductase activity	1.73E-02
102	GO:0001085: RNA polymerase II transcription factor binding	1.93E-02
103	GO:0004791: thioredoxin-disulfide reductase activity	2.03E-02
104	GO:0010181: FMN binding	2.03E-02
105	GO:0015144: carbohydrate transmembrane transporter activity	2.07E-02
106	GO:0005351: sugar:proton symporter activity	2.33E-02
107	GO:0004197: cysteine-type endopeptidase activity	2.35E-02
108	GO:0008194: UDP-glycosyltransferase activity	2.67E-02
109	GO:0016413: O-acetyltransferase activity	2.80E-02
110	GO:0016597: amino acid binding	2.80E-02
111	GO:0009931: calcium-dependent protein serine/threonine kinase activity	3.15E-02
112	GO:0004683: calmodulin-dependent protein kinase activity	3.27E-02
113	GO:0004806: triglyceride lipase activity	3.27E-02
114	GO:0000166: nucleotide binding	3.41E-02
115	GO:0046982: protein heterodimerization activity	3.62E-02
116	GO:0015238: drug transmembrane transporter activity	3.65E-02
117	GO:0005096: GTPase activator activity	3.65E-02
118	GO:0004222: metalloendopeptidase activity	3.77E-02
119	GO:0030145: manganese ion binding	3.90E-02
120	GO:0001228: transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	3.90E-02
121	GO:0016491: oxidoreductase activity	3.94E-02
122	GO:0008233: peptidase activity	4.48E-02
123	GO:0004364: glutathione transferase activity	4.85E-02

Rank	GO Term	Adjusted P value
1	GO:0019822: P4 peroxisome	0.00E+00
2	GO:0005674: transcription factor TFIIF complex	0.00E+00
3	GO:0005829: cytosol	1.63E-08
4	GO:0005886: plasma membrane	8.93E-08
5	GO:0031304: intrinsic component of mitochondrial inner membrane	5.05E-04
6	GO:0005795: Golgi stack	7.89E-04
7	GO:0030139: endocytic vesicle	8.21E-04
8	GO:0005783: endoplasmic reticulum	1.14E-03
9	GO:0031461: cullin-RING ubiquitin ligase complex	1.17E-03
10	GO:0005839: proteasome core complex	1.17E-03
11	GO:0000502: proteasome complex	1.41E-03
12	GO:0000813: ESCRT I complex	1.99E-03
13	GO:0030127: COPII vesicle coat	2.45E-03
14	GO:0016363: nuclear matrix	2.94E-03
15	GO:0031597: cytosolic proteasome complex	2.94E-03
16	GO:0005777: peroxisome	2.97E-03
17	GO:0009524: phragmoplast	3.14E-03
18	GO:0000794: condensed nuclear chromosome	3.47E-03
19	GO:0031595: nuclear proteasome complex	3.47E-03
20	GO:0005794: Golgi apparatus	3.60E-03
21	GO:0030131: clathrin adaptor complex	4.02E-03
22	GO:0030665: clathrin-coated vesicle membrane	5.85E-03
23	GO:0008540: proteasome regulatory particle, base subcomplex	5.85E-03
24	GO:0005819: spindle	6.05E-03
25	GO:0031902: late endosome membrane	6.58E-03
26	GO:0005765: lysosomal membrane	7.20E-03
27	GO:0016602: CCAAT-binding factor complex	8.66E-03
28	GO:0005764: lysosome	9.42E-03
29	GO:0005773: vacuole	9.54E-03
30	GO:0005774: vacuolar membrane	9.72E-03
31	GO:0005635: nuclear envelope	1.03E-02
32	GO:0005834: heterotrimeric G-protein complex	1.22E-02
33	GO:0005905: clathrin-coated pit	1.36E-02
34	GO:0030136: clathrin-coated vesicle	1.73E-02
35	GO:0019898: extrinsic component of membrane	2.14E-02
36	GO:0071944: cell periphery	2.46E-02
37	GO:0000932: P-body	2.91E-02
38	GO:0005667: transcription factor complex	3.15E-02
39	GO:0005618: cell wall	3.31E-02
40	GO:0000151: ubiquitin ligase complex	3.52E-02
41	GO:0009570: chloroplast stroma	3.64E-02
42	GO:0000325: plant-type vacuole	3.90E-02
43	GO:0080008: Cul4-RING E3 ubiquitin ligase complex	4.04E-02