Gene type: Transcription factor Metabolic gene Others DE type: Up Down Slightly_up Slightly_down Mixeded Others

GO Enrichment Analysis of Co-expressed Genes with

AT4G22830

GO-BP
GO-MF
GO-CC
RankGO TermAdjusted P value
1GO:1901918: negative regulation of exoribonuclease activity0.00E+00
2GO:0032194: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate0.00E+00
3GO:0006780: uroporphyrinogen III biosynthetic process0.00E+00
4GO:0033614: chloroplast proton-transporting ATP synthase complex assembly0.00E+00
5GO:0051924: regulation of calcium ion transport0.00E+00
6GO:0006428: isoleucyl-tRNA aminoacylation0.00E+00
7GO:2000042: negative regulation of double-strand break repair via homologous recombination0.00E+00
8GO:0042820: vitamin B6 catabolic process0.00E+00
9GO:0042821: pyridoxal biosynthetic process0.00E+00
10GO:0035970: peptidyl-threonine dephosphorylation0.00E+00
11GO:0046471: phosphatidylglycerol metabolic process0.00E+00
12GO:0018023: peptidyl-lysine trimethylation0.00E+00
13GO:0052865: 1-deoxy-D-xylulose 5-phosphate biosynthetic process0.00E+00
14GO:1905157: positive regulation of photosynthesis0.00E+00
15GO:0097275: cellular ammonia homeostasis0.00E+00
16GO:0015979: photosynthesis1.16E-09
17GO:0015995: chlorophyll biosynthetic process3.86E-09
18GO:0010207: photosystem II assembly5.94E-09
19GO:0009773: photosynthetic electron transport in photosystem I9.80E-08
20GO:1901259: chloroplast rRNA processing1.42E-05
21GO:0010258: NADH dehydrogenase complex (plastoquinone) assembly8.96E-05
22GO:0071484: cellular response to light intensity8.96E-05
23GO:0010114: response to red light1.36E-04
24GO:0010236: plastoquinone biosynthetic process2.36E-04
25GO:0010190: cytochrome b6f complex assembly3.32E-04
26GO:0042549: photosystem II stabilization3.32E-04
27GO:0019288: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway3.32E-04
28GO:0009768: photosynthesis, light harvesting in photosystem I4.13E-04
29GO:0009955: adaxial/abaxial pattern specification4.43E-04
30GO:0000476: maturation of 4.5S rRNA5.34E-04
31GO:0009443: pyridoxal 5'-phosphate salvage5.34E-04
32GO:0000967: rRNA 5'-end processing5.34E-04
33GO:1905039: carboxylic acid transmembrane transport5.34E-04
34GO:1905200: gibberellic acid transmembrane transport5.34E-04
35GO:0080112: seed growth5.34E-04
36GO:0005980: glycogen catabolic process5.34E-04
37GO:0042371: vitamin K biosynthetic process5.34E-04
38GO:0043686: co-translational protein modification5.34E-04
39GO:0043007: maintenance of rDNA5.34E-04
40GO:0034337: RNA folding5.34E-04
41GO:0005991: trehalose metabolic process5.34E-04
42GO:0006353: DNA-templated transcription, termination7.07E-04
43GO:0009657: plastid organization8.61E-04
44GO:0032544: plastid translation8.61E-04
45GO:0006098: pentose-phosphate shunt1.03E-03
46GO:1902326: positive regulation of chlorophyll biosynthetic process1.15E-03
47GO:0018026: peptidyl-lysine monomethylation1.15E-03
48GO:0006898: receptor-mediated endocytosis1.15E-03
49GO:0034755: iron ion transmembrane transport1.15E-03
50GO:0071457: cellular response to ozone1.15E-03
51GO:1904143: positive regulation of carotenoid biosynthetic process1.15E-03
52GO:0034470: ncRNA processing1.15E-03
53GO:0032502: developmental process1.25E-03
54GO:0006782: protoporphyrinogen IX biosynthetic process1.41E-03
55GO:0006954: inflammatory response1.89E-03
56GO:0090391: granum assembly1.89E-03
57GO:0006696: ergosterol biosynthetic process1.89E-03
58GO:0005977: glycogen metabolic process1.89E-03
59GO:0006094: gluconeogenesis2.13E-03
60GO:0009052: pentose-phosphate shunt, non-oxidative branch2.73E-03
61GO:0010731: protein glutathionylation2.73E-03
62GO:0006168: adenine salvage2.73E-03
63GO:1902358: sulfate transmembrane transport2.73E-03
64GO:0045338: farnesyl diphosphate metabolic process2.73E-03
65GO:0006166: purine ribonucleoside salvage2.73E-03
66GO:0006020: inositol metabolic process2.73E-03
67GO:0051085: chaperone mediated protein folding requiring cofactor2.73E-03
68GO:0009152: purine ribonucleotide biosynthetic process2.73E-03
69GO:0046653: tetrahydrofolate metabolic process2.73E-03
70GO:0009658: chloroplast organization2.77E-03
71GO:0010107: potassium ion import3.68E-03
72GO:0015994: chlorophyll metabolic process3.68E-03
73GO:0022622: root system development3.68E-03
74GO:0006546: glycine catabolic process3.68E-03
75GO:0006021: inositol biosynthetic process3.68E-03
76GO:0071483: cellular response to blue light3.68E-03
77GO:0010021: amylopectin biosynthetic process3.68E-03
78GO:0071486: cellular response to high light intensity3.68E-03
79GO:0019464: glycine decarboxylation via glycine cleavage system3.68E-03
80GO:0009765: photosynthesis, light harvesting3.68E-03
81GO:0061077: chaperone-mediated protein folding4.06E-03
82GO:0006465: signal peptide processing4.72E-03
83GO:0071493: cellular response to UV-B4.72E-03
84GO:0098719: sodium ion import across plasma membrane4.72E-03
85GO:0006564: L-serine biosynthetic process4.72E-03
86GO:0009904: chloroplast accumulation movement4.72E-03
87GO:0031365: N-terminal protein amino acid modification4.72E-03
88GO:0044209: AMP salvage4.72E-03
89GO:1902456: regulation of stomatal opening5.86E-03
90GO:0006086: acetyl-CoA biosynthetic process from pyruvate5.86E-03
91GO:0009643: photosynthetic acclimation5.86E-03
92GO:0000741: karyogamy5.86E-03
93GO:0009228: thiamine biosynthetic process5.86E-03
94GO:0046855: inositol phosphate dephosphorylation5.86E-03
95GO:0010304: PSII associated light-harvesting complex II catabolic process5.86E-03
96GO:0006751: glutathione catabolic process5.86E-03
97GO:0009958: positive gravitropism6.68E-03
98GO:0009741: response to brassinosteroid6.68E-03
99GO:0042372: phylloquinone biosynthetic process7.07E-03
100GO:0042026: protein refolding7.07E-03
101GO:0048280: vesicle fusion with Golgi apparatus7.07E-03
102GO:0009903: chloroplast avoidance movement7.07E-03
103GO:0010189: vitamin E biosynthetic process7.07E-03
104GO:0071333: cellular response to glucose stimulus7.07E-03
105GO:0019252: starch biosynthetic process7.72E-03
106GO:0010196: nonphotochemical quenching8.37E-03
107GO:0009645: response to low light intensity stimulus8.37E-03
108GO:0008272: sulfate transport8.37E-03
109GO:0009769: photosynthesis, light harvesting in photosystem II8.37E-03
110GO:0032880: regulation of protein localization8.37E-03
111GO:0009772: photosynthetic electron transport in photosystem II8.37E-03
112GO:0055114: oxidation-reduction process8.99E-03
113GO:1901657: glycosyl compound metabolic process9.43E-03
114GO:0006810: transport9.62E-03
115GO:0009642: response to light intensity9.75E-03
116GO:0010078: maintenance of root meristem identity9.75E-03
117GO:0042255: ribosome assembly9.75E-03
118GO:0070413: trehalose metabolism in response to stress9.75E-03
119GO:0055075: potassium ion homeostasis9.75E-03
120GO:0052543: callose deposition in cell wall9.75E-03
121GO:0048564: photosystem I assembly9.75E-03
122GO:0019430: removal of superoxide radicals1.12E-02
123GO:0043562: cellular response to nitrogen levels1.12E-02
124GO:0071482: cellular response to light stimulus1.12E-02
125GO:0015996: chlorophyll catabolic process1.12E-02
126GO:0010027: thylakoid membrane organization1.20E-02
127GO:0009821: alkaloid biosynthetic process1.27E-02
128GO:0010206: photosystem II repair1.27E-02
129GO:0090333: regulation of stomatal closure1.27E-02
130GO:0046916: cellular transition metal ion homeostasis1.27E-02
131GO:0006783: heme biosynthetic process1.27E-02
132GO:0046685: response to arsenic-containing substance1.27E-02
133GO:0051453: regulation of intracellular pH1.43E-02
134GO:0005982: starch metabolic process1.43E-02
135GO:0031146: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.43E-02
136GO:0006779: porphyrin-containing compound biosynthetic process1.43E-02
137GO:0018298: protein-chromophore linkage1.57E-02
138GO:0006896: Golgi to vacuole transport1.60E-02
139GO:0045036: protein targeting to chloroplast1.60E-02
140GO:0009641: shade avoidance1.60E-02
141GO:0006949: syncytium formation1.60E-02
142GO:0009813: flavonoid biosynthetic process1.65E-02
143GO:0010218: response to far red light1.74E-02
144GO:0019684: photosynthesis, light reaction1.77E-02
145GO:0043085: positive regulation of catalytic activity1.77E-02
146GO:0006879: cellular iron ion homeostasis1.77E-02
147GO:0015770: sucrose transport1.77E-02
148GO:0006415: translational termination1.77E-02
149GO:0009684: indoleacetic acid biosynthetic process1.77E-02
150GO:0048527: lateral root development1.82E-02
151GO:0009735: response to cytokinin1.85E-02
152GO:0016024: CDP-diacylglycerol biosynthetic process1.95E-02
153GO:0006790: sulfur compound metabolic process1.95E-02
154GO:0009637: response to blue light2.00E-02
155GO:0009853: photorespiration2.00E-02
156GO:0010588: cotyledon vascular tissue pattern formation2.14E-02
157GO:2000012: regulation of auxin polar transport2.14E-02
158GO:0009767: photosynthetic electron transport chain2.14E-02
159GO:0009416: response to light stimulus2.16E-02
160GO:0010143: cutin biosynthetic process2.33E-02
161GO:0007015: actin filament organization2.33E-02
162GO:0010223: secondary shoot formation2.33E-02
163GO:0048467: gynoecium development2.33E-02
164GO:0032259: methylation2.47E-02
165GO:0019853: L-ascorbic acid biosynthetic process2.53E-02
166GO:0009901: anther dehiscence2.53E-02
167GO:0016042: lipid catabolic process2.53E-02
168GO:0046854: phosphatidylinositol phosphorylation2.53E-02
169GO:0051707: response to other organism2.58E-02
170GO:0046686: response to cadmium ion2.69E-02
171GO:0006636: unsaturated fatty acid biosynthetic process2.74E-02
172GO:0080147: root hair cell development2.94E-02
173GO:0005992: trehalose biosynthetic process2.94E-02
174GO:0006855: drug transmembrane transport3.01E-02
175GO:0006418: tRNA aminoacylation for protein translation3.16E-02
176GO:0019915: lipid storage3.38E-02
177GO:0009269: response to desiccation3.38E-02
178GO:0016114: terpenoid biosynthetic process3.38E-02
179GO:0006364: rRNA processing3.48E-02
180GO:0016226: iron-sulfur cluster assembly3.61E-02
181GO:0030433: ubiquitin-dependent ERAD pathway3.61E-02
182GO:0006730: one-carbon metabolic process3.61E-02
183GO:0007005: mitochondrion organization3.61E-02
184GO:0019748: secondary metabolic process3.61E-02
185GO:0009831: plant-type cell wall modification involved in multidimensional cell growth3.83E-02
186GO:0071215: cellular response to abscisic acid stimulus3.83E-02
187GO:0009686: gibberellin biosynthetic process3.83E-02
188GO:0006012: galactose metabolic process3.83E-02
189GO:0042254: ribosome biogenesis3.95E-02
190GO:0009306: protein secretion4.07E-02
191GO:0006096: glycolytic process4.10E-02
192GO:0048367: shoot system development4.23E-02
193GO:0008284: positive regulation of cell proliferation4.31E-02
194GO:0042147: retrograde transport, endosome to Golgi4.31E-02
195GO:0016117: carotenoid biosynthetic process4.31E-02
196GO:0080022: primary root development4.55E-02
197GO:0000413: protein peptidyl-prolyl isomerization4.55E-02
198GO:0010087: phloem or xylem histogenesis4.55E-02
199GO:0006885: regulation of pH4.80E-02
200GO:0071472: cellular response to salt stress4.80E-02
201GO:0006662: glycerol ether metabolic process4.80E-02
202GO:0010197: polar nucleus fusion4.80E-02
203GO:0010182: sugar mediated signaling pathway4.80E-02
204GO:0010268: brassinosteroid homeostasis4.80E-02
RankGO TermAdjusted P value
1GO:0010349: L-galactose dehydrogenase activity0.00E+00
2GO:0050236: pyridoxine:NADP 4-dehydrogenase activity0.00E+00
3GO:0090711: FMN hydrolase activity0.00E+00
4GO:0102550: 2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity0.00E+00
5GO:0050518: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity0.00E+00
6GO:0046428: 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity0.00E+00
7GO:0004822: isoleucine-tRNA ligase activity0.00E+00
8GO:0046408: chlorophyll synthetase activity0.00E+00
9GO:0004852: uroporphyrinogen-III synthase activity0.00E+00
10GO:0008942: nitrite reductase [NAD(P)H] activity0.00E+00
11GO:0052637: delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity0.00E+00
12GO:0019843: rRNA binding1.60E-06
13GO:0005528: FK506 binding2.40E-05
14GO:0016851: magnesium chelatase activity8.96E-05
15GO:0016655: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor1.54E-04
16GO:0003755: peptidyl-prolyl cis-trans isomerase activity1.87E-04
17GO:0031409: pigment binding3.14E-04
18GO:0004332: fructose-bisphosphate aldolase activity3.32E-04
19GO:0008184: glycogen phosphorylase activity5.34E-04
20GO:0051777: ent-kaurenoate oxidase activity5.34E-04
21GO:0004856: xylulokinase activity5.34E-04
22GO:0004645: phosphorylase activity5.34E-04
23GO:0034256: chlorophyll(ide) b reductase activity5.34E-04
24GO:0004853: uroporphyrinogen decarboxylase activity5.34E-04
25GO:0042586: peptide deformylase activity5.34E-04
26GO:0030785: [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity5.34E-04
27GO:0045486: naringenin 3-dioxygenase activity5.34E-04
28GO:0051741: 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity5.34E-04
29GO:1905201: gibberellin transmembrane transporter activity5.34E-04
30GO:0004033: aldo-keto reductase (NADP) activity7.07E-04
31GO:0080097: L-tryptophan:pyruvate aminotransferase activity1.15E-03
32GO:0016630: protochlorophyllide reductase activity1.15E-03
33GO:0047158: sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity1.15E-03
34GO:0008934: inositol monophosphate 1-phosphatase activity1.15E-03
35GO:0019172: glyoxalase III activity1.15E-03
36GO:0019156: isoamylase activity1.15E-03
37GO:0052833: inositol monophosphate 4-phosphatase activity1.15E-03
38GO:0004310: farnesyl-diphosphate farnesyltransferase activity1.15E-03
39GO:0047746: chlorophyllase activity1.15E-03
40GO:0003839: gamma-glutamylcyclotransferase activity1.15E-03
41GO:0050362: L-tryptophan:2-oxoglutarate aminotransferase activity1.15E-03
42GO:0004617: phosphoglycerate dehydrogenase activity1.15E-03
43GO:0004047: aminomethyltransferase activity1.15E-03
44GO:0008661: 1-deoxy-D-xylulose-5-phosphate synthase activity1.15E-03
45GO:0052832: inositol monophosphate 3-phosphatase activity1.15E-03
46GO:0033201: alpha-1,4-glucan synthase activity1.15E-03
47GO:0015386: potassium:proton antiporter activity1.63E-03
48GO:0047372: acylglycerol lipase activity1.63E-03
49GO:0004373: glycogen (starch) synthase activity1.89E-03
50GO:0002161: aminoacyl-tRNA editing activity1.89E-03
51GO:0004148: dihydrolipoyl dehydrogenase activity1.89E-03
52GO:0004751: ribose-5-phosphate isomerase activity1.89E-03
53GO:0045174: glutathione dehydrogenase (ascorbate) activity1.89E-03
54GO:0016742: hydroxymethyl-, formyl- and related transferase activity1.89E-03
55GO:0070402: NADPH binding1.89E-03
56GO:0008864: formyltetrahydrofolate deformylase activity1.89E-03
57GO:0016168: chlorophyll binding1.98E-03
58GO:0019201: nucleotide kinase activity2.73E-03
59GO:0003999: adenine phosphoribosyltransferase activity2.73E-03
60GO:0016149: translation release factor activity, codon specific2.73E-03
61GO:0022890: inorganic cation transmembrane transporter activity2.73E-03
62GO:0003825: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity2.73E-03
63GO:0004375: glycine dehydrogenase (decarboxylating) activity2.73E-03
64GO:0016491: oxidoreductase activity2.82E-03
65GO:0045430: chalcone isomerase activity3.68E-03
66GO:0009011: starch synthase activity3.68E-03
67GO:0004659: prenyltransferase activity3.68E-03
68GO:0016279: protein-lysine N-methyltransferase activity3.68E-03
69GO:0003959: NADPH dehydrogenase activity4.72E-03
70GO:0016846: carbon-sulfur lyase activity4.72E-03
71GO:0016773: phosphotransferase activity, alcohol group as acceptor4.72E-03
72GO:0003727: single-stranded RNA binding5.28E-03
73GO:0004556: alpha-amylase activity5.86E-03
74GO:0004462: lactoylglutathione lyase activity5.86E-03
75GO:0004366: glycerol-3-phosphate O-acyltransferase activity5.86E-03
76GO:0004784: superoxide dismutase activity5.86E-03
77GO:0015081: sodium ion transmembrane transporter activity5.86E-03
78GO:0090447: glycerol-3-phosphate 2-O-acyltransferase activity5.86E-03
79GO:0045156: electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity7.07E-03
80GO:0004017: adenylate kinase activity7.07E-03
81GO:0008441: 3'(2'),5'-bisphosphate nucleotidase activity7.07E-03
82GO:0004723: calcium-dependent protein serine/threonine phosphatase activity7.07E-03
83GO:0048038: quinone binding8.27E-03
84GO:0008168: methyltransferase activity1.00E-02
85GO:0016791: phosphatase activity1.00E-02
86GO:0016788: hydrolase activity, acting on ester bonds1.10E-02
87GO:0008271: secondary active sulfate transmembrane transporter activity1.12E-02
88GO:0046914: transition metal ion binding1.12E-02
89GO:0003747: translation release factor activity1.27E-02
90GO:0102483: scopolin beta-glucosidase activity1.42E-02
91GO:0005381: iron ion transmembrane transporter activity1.43E-02
92GO:0016844: strictosidine synthase activity1.43E-02
93GO:0008047: enzyme activator activity1.60E-02
94GO:0015238: drug transmembrane transporter activity1.65E-02
95GO:0008515: sucrose transmembrane transporter activity1.77E-02
96GO:0008559: xenobiotic-transporting ATPase activity1.77E-02
97GO:0044183: protein binding involved in protein folding1.77E-02
98GO:0003735: structural constituent of ribosome1.93E-02
99GO:0000049: tRNA binding1.95E-02
100GO:0015116: sulfate transmembrane transporter activity1.95E-02
101GO:0008378: galactosyltransferase activity1.95E-02
102GO:0003993: acid phosphatase activity2.09E-02
103GO:0003725: double-stranded RNA binding2.14E-02
104GO:0004022: alcohol dehydrogenase (NAD) activity2.14E-02
105GO:0004089: carbonate dehydratase activity2.14E-02
106GO:0031072: heat shock protein binding2.14E-02
107GO:0008422: beta-glucosidase activity2.18E-02
108GO:0016787: hydrolase activity2.27E-02
109GO:0042973: glucan endo-1,3-beta-D-glucosidase activity2.33E-02
110GO:0008266: poly(U) RNA binding2.33E-02
111GO:0008083: growth factor activity2.33E-02
112GO:0005509: calcium ion binding2.40E-02
113GO:0051119: sugar transmembrane transporter activity2.53E-02
114GO:0004185: serine-type carboxypeptidase activity2.58E-02
115GO:0003743: translation initiation factor activity2.72E-02
116GO:0043621: protein self-association2.79E-02
117GO:0051537: 2 iron, 2 sulfur cluster binding2.79E-02
118GO:0051536: iron-sulfur cluster binding2.94E-02
119GO:0031418: L-ascorbic acid binding2.94E-02
120GO:0015079: potassium ion transmembrane transporter activity3.16E-02
121GO:0003690: double-stranded DNA binding3.60E-02
122GO:0047134: protein-disulfide reductase activity4.31E-02
123GO:0004812: aminoacyl-tRNA ligase activity4.31E-02
124GO:0003713: transcription coactivator activity4.80E-02
125GO:0005525: GTP binding4.91E-02
126GO:0051082: unfolded protein binding4.92E-02
RankGO TermAdjusted P value
1GO:0009575: chromoplast stroma0.00E+00
2GO:0009571: proplastid stroma0.00E+00
3GO:0009507: chloroplast2.48E-54
4GO:0009535: chloroplast thylakoid membrane4.35E-32
5GO:0009570: chloroplast stroma4.25E-24
6GO:0009534: chloroplast thylakoid2.66E-23
7GO:0009579: thylakoid1.70E-18
8GO:0009543: chloroplast thylakoid lumen5.82E-17
9GO:0009941: chloroplast envelope2.51E-16
10GO:0031977: thylakoid lumen1.81E-12
11GO:0010598: NAD(P)H dehydrogenase complex (plastoquinone)2.19E-10
12GO:0031969: chloroplast membrane6.58E-09
13GO:0009654: photosystem II oxygen evolving complex2.74E-08
14GO:0019898: extrinsic component of membrane8.13E-06
15GO:0010287: plastoglobule1.47E-05
16GO:0010007: magnesium chelatase complex4.21E-05
17GO:0030095: chloroplast photosystem II2.30E-04
18GO:0030076: light-harvesting complex2.70E-04
19GO:0005787: signal peptidase complex5.34E-04
20GO:0009344: nitrite reductase complex [NAD(P)H]5.34E-04
21GO:0009547: plastid ribosome5.34E-04
22GO:0005840: ribosome5.49E-04
23GO:0009522: photosystem I9.67E-04
24GO:0033281: TAT protein transport complex1.89E-03
25GO:0009508: plastid chromosome2.13E-03
26GO:0005960: glycine cleavage complex2.73E-03
27GO:0005623: cell3.48E-03
28GO:0009517: PSII associated light-harvesting complex II3.68E-03
29GO:0042651: thylakoid membrane3.69E-03
30GO:0009840: chloroplastic endopeptidase Clp complex7.07E-03
31GO:0009523: photosystem II7.72E-03
32GO:0031982: vesicle9.75E-03
33GO:0012507: ER to Golgi transport vesicle membrane9.75E-03
34GO:0009501: amyloplast9.75E-03
35GO:0009295: nucleoid1.07E-02
36GO:0009539: photosystem II reaction center1.12E-02
37GO:0005763: mitochondrial small ribosomal subunit1.27E-02
38GO:0000311: plastid large ribosomal subunit1.95E-02
39GO:0032040: small-subunit processome1.95E-02
40GO:0015935: small ribosomal subunit3.38E-02
41GO:0009532: plastid stroma3.38E-02
42GO:0009536: plastid4.05E-02
43GO:0009706: chloroplast inner membrane4.92E-02
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Gene type



Gene DE type