Gene type: Transcription factor Metabolic gene Others DE type: Up Down Slightly_up Slightly_down Mixeded Others

GO Enrichment Analysis of Co-expressed Genes with

AT1G53750

GO-BP
GO-MF
GO-CC
RankGO TermAdjusted P value
1GO:0009991: response to extracellular stimulus0.00E+00
2GO:0006593: ornithine catabolic process0.00E+00
3GO:0032780: negative regulation of ATPase activity0.00E+00
4GO:0006482: protein demethylation0.00E+00
5GO:0010111: glyoxysome organization0.00E+00
6GO:0017186: peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase0.00E+00
7GO:0046109: uridine biosynthetic process0.00E+00
8GO:0010360: negative regulation of anion channel activity0.00E+00
9GO:1901017: negative regulation of potassium ion transmembrane transporter activity0.00E+00
10GO:0007141: male meiosis I0.00E+00
11GO:2000541: positive regulation of protein geranylgeranylation0.00E+00
12GO:0035269: protein O-linked mannosylation0.00E+00
13GO:0048227: plasma membrane to endosome transport0.00E+00
14GO:0033542: fatty acid beta-oxidation, unsaturated, even number0.00E+00
15GO:0033539: fatty acid beta-oxidation using acyl-CoA dehydrogenase0.00E+00
16GO:0045185: maintenance of protein location0.00E+00
17GO:0006631: fatty acid metabolic process1.05E-05
18GO:0001676: long-chain fatty acid metabolic process2.63E-05
19GO:0051315: attachment of mitotic spindle microtubules to kinetochore2.65E-04
20GO:0071586: CAAX-box protein processing2.65E-04
21GO:0019628: urate catabolic process2.65E-04
22GO:0006422: aspartyl-tRNA aminoacylation2.65E-04
23GO:0046901: tetrahydrofolylpolyglutamate biosynthetic process2.65E-04
24GO:0006481: C-terminal protein methylation2.65E-04
25GO:0010482: regulation of epidermal cell division2.65E-04
26GO:0033306: phytol metabolic process2.65E-04
27GO:0003400: regulation of COPII vesicle coating2.65E-04
28GO:1902361: mitochondrial pyruvate transmembrane transport2.65E-04
29GO:0019544: arginine catabolic process to glutamate2.65E-04
30GO:0007093: mitotic cell cycle checkpoint2.65E-04
31GO:0034214: protein hexamerization2.65E-04
32GO:0006144: purine nucleobase metabolic process2.65E-04
33GO:0080120: CAAX-box protein maturation2.65E-04
34GO:0046686: response to cadmium ion2.68E-04
35GO:0009699: phenylpropanoid biosynthetic process3.10E-04
36GO:0006511: ubiquitin-dependent protein catabolic process4.42E-04
37GO:0015824: proline transport5.83E-04
38GO:0006850: mitochondrial pyruvate transport5.83E-04
39GO:1904961: quiescent center organization5.83E-04
40GO:0019441: tryptophan catabolic process to kynurenine5.83E-04
41GO:0051258: protein polymerization5.83E-04
42GO:0060919: auxin influx5.83E-04
43GO:0097054: L-glutamate biosynthetic process5.83E-04
44GO:0009156: ribonucleoside monophosphate biosynthetic process5.83E-04
45GO:0019395: fatty acid oxidation5.83E-04
46GO:0031648: protein destabilization5.83E-04
47GO:0015914: phospholipid transport5.83E-04
48GO:0000266: mitochondrial fission6.85E-04
49GO:0046777: protein autophosphorylation7.19E-04
50GO:0048767: root hair elongation7.43E-04
51GO:0048281: inflorescence morphogenesis9.47E-04
52GO:0010359: regulation of anion channel activity9.47E-04
53GO:0051646: mitochondrion localization9.47E-04
54GO:0002230: positive regulation of defense response to virus by host9.47E-04
55GO:0055114: oxidation-reduction process1.25E-03
56GO:0006537: glutamate biosynthetic process1.35E-03
57GO:0009052: pentose-phosphate shunt, non-oxidative branch1.35E-03
58GO:0072583: clathrin-dependent endocytosis1.35E-03
59GO:1902290: positive regulation of defense response to oomycetes1.35E-03
60GO:2000114: regulation of establishment of cell polarity1.35E-03
61GO:0031408: oxylipin biosynthetic process1.44E-03
62GO:0019676: ammonia assimilation cycle1.81E-03
63GO:0033320: UDP-D-xylose biosynthetic process1.81E-03
64GO:0010363: regulation of plant-type hypersensitive response1.81E-03
65GO:0051567: histone H3-K9 methylation1.81E-03
66GO:0009165: nucleotide biosynthetic process1.81E-03
67GO:0006542: glutamine biosynthetic process1.81E-03
68GO:0070534: protein K63-linked ubiquitination1.81E-03
69GO:0018344: protein geranylgeranylation2.31E-03
70GO:0006656: phosphatidylcholine biosynthetic process2.31E-03
71GO:0007094: mitotic spindle assembly checkpoint2.31E-03
72GO:0048232: male gamete generation2.85E-03
73GO:0070814: hydrogen sulfide biosynthetic process2.85E-03
74GO:0042732: D-xylose metabolic process2.85E-03
75GO:1902456: regulation of stomatal opening2.85E-03
76GO:1900425: negative regulation of defense response to bacterium2.85E-03
77GO:0010315: auxin efflux2.85E-03
78GO:0006574: valine catabolic process2.85E-03
79GO:0006014: D-ribose metabolic process2.85E-03
80GO:0045899: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly2.85E-03
81GO:0019243: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione2.85E-03
82GO:0006561: proline biosynthetic process2.85E-03
83GO:0006301: postreplication repair2.85E-03
84GO:0006635: fatty acid beta-oxidation2.90E-03
85GO:0007264: small GTPase mediated signal transduction3.10E-03
86GO:0052033: pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response3.43E-03
87GO:0006614: SRP-dependent cotranslational protein targeting to membrane4.04E-03
88GO:1900057: positive regulation of leaf senescence4.04E-03
89GO:0009058: biosynthetic process4.18E-03
90GO:0009788: negative regulation of abscisic acid-activated signaling pathway4.43E-03
91GO:0009816: defense response to bacterium, incompatible interaction4.43E-03
92GO:0016559: peroxisome fission4.69E-03
93GO:0009819: drought recovery4.69E-03
94GO:0006605: protein targeting4.69E-03
95GO:0019375: galactolipid biosynthetic process4.69E-03
96GO:2000070: regulation of response to water deprivation4.69E-03
97GO:0048766: root hair initiation4.69E-03
98GO:0006506: GPI anchor biosynthetic process4.69E-03
99GO:0006102: isocitrate metabolic process4.69E-03
100GO:0006633: fatty acid biosynthetic process5.22E-03
101GO:0030968: endoplasmic reticulum unfolded protein response5.37E-03
102GO:0015031: protein transport5.80E-03
103GO:0010150: leaf senescence5.88E-03
104GO:0090305: nucleic acid phosphodiester bond hydrolysis6.09E-03
105GO:0000184: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.09E-03
106GO:0006098: pentose-phosphate shunt6.09E-03
107GO:0090333: regulation of stomatal closure6.09E-03
108GO:0019432: triglyceride biosynthetic process6.09E-03
109GO:1900426: positive regulation of defense response to bacterium6.83E-03
110GO:2000280: regulation of root development6.83E-03
111GO:0010449: root meristem growth6.83E-03
112GO:0006468: protein phosphorylation7.17E-03
113GO:0007064: mitotic sister chromatid cohesion7.61E-03
114GO:0006896: Golgi to vacuole transport7.61E-03
115GO:0000103: sulfate assimilation7.61E-03
116GO:0051026: chiasma assembly7.61E-03
117GO:0019538: protein metabolic process7.61E-03
118GO:0043069: negative regulation of programmed cell death7.61E-03
119GO:0072593: reactive oxygen species metabolic process8.42E-03
120GO:0018119: peptidyl-cysteine S-nitrosylation8.42E-03
121GO:0048765: root hair cell differentiation8.42E-03
122GO:0051707: response to other organism8.94E-03
123GO:0006890: retrograde vesicle-mediated transport, Golgi to ER9.26E-03
124GO:0000209: protein polyubiquitination9.30E-03
125GO:0032436: positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.01E-02
126GO:0006807: nitrogen compound metabolic process1.01E-02
127GO:0055046: microgametogenesis1.01E-02
128GO:0042787: protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.08E-02
129GO:0010540: basipetal auxin transport1.10E-02
130GO:0009266: response to temperature stimulus1.10E-02
131GO:0007034: vacuolar transport1.10E-02
132GO:0009887: animal organ morphogenesis1.10E-02
133GO:0009225: nucleotide-sugar metabolic process1.20E-02
134GO:0007031: peroxisome organization1.20E-02
135GO:0010167: response to nitrate1.20E-02
136GO:0010039: response to iron ion1.20E-02
137GO:0070588: calcium ion transmembrane transport1.20E-02
138GO:0010053: root epidermal cell differentiation1.20E-02
139GO:0051603: proteolysis involved in cellular protein catabolic process1.25E-02
140GO:0034976: response to endoplasmic reticulum stress1.29E-02
141GO:0080167: response to karrikin1.35E-02
142GO:0009116: nucleoside metabolic process1.39E-02
143GO:2000377: regulation of reactive oxygen species metabolic process1.39E-02
144GO:0009651: response to salt stress1.47E-02
145GO:0048367: shoot system development1.48E-02
146GO:0010026: trichome differentiation1.49E-02
147GO:0009695: jasmonic acid biosynthetic process1.49E-02
148GO:0009737: response to abscisic acid1.58E-02
149GO:0007131: reciprocal meiotic recombination1.70E-02
150GO:0030433: ubiquitin-dependent ERAD pathway1.70E-02
151GO:0006730: one-carbon metabolic process1.70E-02
152GO:0007005: mitochondrion organization1.70E-02
153GO:0031348: negative regulation of defense response1.70E-02
154GO:0009561: megagametogenesis1.92E-02
155GO:0009306: protein secretion1.92E-02
156GO:0009789: positive regulation of abscisic acid-activated signaling pathway2.03E-02
157GO:0016310: phosphorylation2.06E-02
158GO:0010154: fruit development2.26E-02
159GO:0048364: root development2.33E-02
160GO:0006623: protein targeting to vacuole2.51E-02
161GO:0009749: response to glucose2.51E-02
162GO:0019252: starch biosynthetic process2.51E-02
163GO:0008654: phospholipid biosynthetic process2.51E-02
164GO:0071554: cell wall organization or biogenesis2.63E-02
165GO:0002229: defense response to oomycetes2.63E-02
166GO:0010193: response to ozone2.63E-02
167GO:0010583: response to cyclopentenone2.76E-02
168GO:0009630: gravitropism2.76E-02
169GO:0030163: protein catabolic process2.88E-02
170GO:0006464: cellular protein modification process3.02E-02
171GO:0006914: autophagy3.02E-02
172GO:0006310: DNA recombination3.02E-02
173GO:0006904: vesicle docking involved in exocytosis3.15E-02
174GO:0016579: protein deubiquitination3.28E-02
175GO:0043161: proteasome-mediated ubiquitin-dependent protein catabolic process3.33E-02
176GO:0006470: protein dephosphorylation3.41E-02
177GO:0007166: cell surface receptor signaling pathway3.41E-02
178GO:0042128: nitrate assimilation3.70E-02
179GO:0006979: response to oxidative stress3.70E-02
180GO:0006950: response to stress3.84E-02
181GO:0006888: ER to Golgi vesicle-mediated transport3.84E-02
182GO:0009817: defense response to fungus, incompatible interaction4.13E-02
183GO:0030244: cellulose biosynthetic process4.13E-02
184GO:0009738: abscisic acid-activated signaling pathway4.32E-02
185GO:0006499: N-terminal protein myristoylation4.43E-02
186GO:0009910: negative regulation of flower development4.58E-02
187GO:0048527: lateral root development4.58E-02
188GO:0010119: regulation of stomatal movement4.58E-02
189GO:0010043: response to zinc ion4.58E-02
190GO:0007568: aging4.58E-02
191GO:0006865: amino acid transport4.73E-02
192GO:0035556: intracellular signal transduction4.80E-02
193GO:0009867: jasmonic acid mediated signaling pathway4.88E-02
194GO:0045087: innate immune response4.88E-02
195GO:0016051: carbohydrate biosynthetic process4.88E-02
RankGO TermAdjusted P value
1GO:0004587: ornithine-oxo-acid transaminase activity0.00E+00
2GO:0050269: coniferyl-aldehyde dehydrogenase activity0.00E+00
3GO:0046424: ferulate 5-hydroxylase activity0.00E+00
4GO:0015930: glutamate synthase activity0.00E+00
5GO:0009940: amino-terminal vacuolar sorting propeptide binding0.00E+00
6GO:0016857: racemase and epimerase activity, acting on carbohydrates and derivatives0.00E+00
7GO:0051723: protein methylesterase activity0.00E+00
8GO:0005092: GDP-dissociation inhibitor activity0.00E+00
9GO:0004846: urate oxidase activity0.00E+00
10GO:0042030: ATPase inhibitor activity0.00E+00
11GO:0016603: glutaminyl-peptide cyclotransferase activity0.00E+00
12GO:0102391: decanoate--CoA ligase activity2.36E-06
13GO:0004467: long-chain fatty acid-CoA ligase activity3.81E-06
14GO:0005093: Rab GDP-dissociation inhibitor activity1.17E-05
15GO:0005524: ATP binding4.99E-05
16GO:0004029: aldehyde dehydrogenase (NAD) activity1.10E-04
17GO:0016491: oxidoreductase activity1.62E-04
18GO:0004815: aspartate-tRNA ligase activity2.65E-04
19GO:0004105: choline-phosphate cytidylyltransferase activity2.65E-04
20GO:0005090: Sar guanyl-nucleotide exchange factor activity2.65E-04
21GO:0008802: betaine-aldehyde dehydrogenase activity2.65E-04
22GO:0080023: 3R-hydroxyacyl-CoA dehydratase activity2.65E-04
23GO:0010209: vacuolar sorting signal binding2.65E-04
24GO:0016041: glutamate synthase (ferredoxin) activity2.65E-04
25GO:0004671: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity2.65E-04
26GO:0003924: GTPase activity2.78E-04
27GO:0004028: 3-chloroallyl aldehyde dehydrogenase activity4.44E-04
28GO:0004326: tetrahydrofolylpolyglutamate synthase activity5.83E-04
29GO:0004582: dolichyl-phosphate beta-D-mannosyltransferase activity5.83E-04
30GO:0004750: ribulose-phosphate 3-epimerase activity5.83E-04
31GO:0004061: arylformamidase activity5.83E-04
32GO:0015036: disulfide oxidoreductase activity5.83E-04
33GO:0004450: isocitrate dehydrogenase (NADP+) activity5.83E-04
34GO:0003988: acetyl-CoA C-acyltransferase activity5.83E-04
35GO:0005096: GTPase activator activity7.43E-04
36GO:0004674: protein serine/threonine kinase activity8.00E-04
37GO:0008442: 3-hydroxyisobutyrate dehydrogenase activity9.47E-04
38GO:0004324: ferredoxin-NADP+ reductase activity9.47E-04
39GO:0004180: carboxypeptidase activity9.47E-04
40GO:0005047: signal recognition particle binding9.47E-04
41GO:0015193: L-proline transmembrane transporter activity9.47E-04
42GO:0004751: ribose-5-phosphate isomerase activity9.47E-04
43GO:0050833: pyruvate transmembrane transporter activity9.47E-04
44GO:0004781: sulfate adenylyltransferase (ATP) activity9.47E-04
45GO:0016805: dipeptidase activity9.47E-04
46GO:0004749: ribose phosphate diphosphokinase activity1.35E-03
47GO:0008276: protein methyltransferase activity1.35E-03
48GO:0004416: hydroxyacylglutathione hydrolase activity1.35E-03
49GO:0016656: monodehydroascorbate reductase (NADH) activity1.35E-03
50GO:0004300: enoyl-CoA hydratase activity1.35E-03
51GO:0003995: acyl-CoA dehydrogenase activity1.81E-03
52GO:0010328: auxin influx transmembrane transporter activity1.81E-03
53GO:0005546: phosphatidylinositol-4,5-bisphosphate binding2.31E-03
54GO:0016702: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen2.31E-03
55GO:0005496: steroid binding2.31E-03
56GO:0017137: Rab GTPase binding2.31E-03
57GO:0051538: 3 iron, 4 sulfur cluster binding2.31E-03
58GO:0004356: glutamate-ammonia ligase activity2.31E-03
59GO:0005525: GTP binding2.40E-03
60GO:0016301: kinase activity2.81E-03
61GO:0048040: UDP-glucuronate decarboxylase activity2.85E-03
62GO:0004526: ribonuclease P activity2.85E-03
63GO:0004069: L-aspartate:2-oxoglutarate aminotransferase activity2.85E-03
64GO:0080130: L-phenylalanine:2-oxoglutarate aminotransferase activity2.85E-03
65GO:0036402: proteasome-activating ATPase activity2.85E-03
66GO:0051020: GTPase binding3.43E-03
67GO:0070403: NAD+ binding3.43E-03
68GO:0008195: phosphatidate phosphatase activity3.43E-03
69GO:0004616: phosphogluconate dehydrogenase (decarboxylating) activity3.43E-03
70GO:0004144: diacylglycerol O-acyltransferase activity3.43E-03
71GO:0004747: ribokinase activity3.43E-03
72GO:0008113: peptide-methionine (S)-S-oxide reductase activity3.43E-03
73GO:0008235: metalloexopeptidase activity4.04E-03
74GO:0102425: myricetin 3-O-glucosyltransferase activity4.04E-03
75GO:0102360: daphnetin 3-O-glucosyltransferase activity4.04E-03
76GO:0003824: catalytic activity4.35E-03
77GO:0047893: flavonol 3-O-glucosyltransferase activity4.69E-03
78GO:0004033: aldo-keto reductase (NADP) activity4.69E-03
79GO:0008865: fructokinase activity4.69E-03
80GO:0008757: S-adenosylmethionine-dependent methyltransferase activity5.20E-03
81GO:0008236: serine-type peptidase activity5.20E-03
82GO:0004630: phospholipase D activity5.37E-03
83GO:0070290: N-acylphosphatidylethanolamine-specific phospholipase D activity5.37E-03
84GO:0071949: FAD binding6.09E-03
85GO:0009815: 1-aminocyclopropane-1-carboxylate oxidase activity6.09E-03
86GO:0004743: pyruvate kinase activity6.83E-03
87GO:0047617: acyl-CoA hydrolase activity6.83E-03
88GO:0030955: potassium ion binding6.83E-03
89GO:0008171: O-methyltransferase activity7.61E-03
90GO:0004177: aminopeptidase activity8.42E-03
91GO:0008559: xenobiotic-transporting ATPase activity8.42E-03
92GO:0000287: magnesium ion binding1.00E-02
93GO:0005388: calcium-transporting ATPase activity1.01E-02
94GO:0010329: auxin efflux transmembrane transporter activity1.01E-02
95GO:0051287: NAD binding1.08E-02
96GO:0031624: ubiquitin conjugating enzyme binding1.10E-02
97GO:0004175: endopeptidase activity1.10E-02
98GO:0017025: TBP-class protein binding1.20E-02
99GO:0050660: flavin adenine dinucleotide binding1.23E-02
100GO:0043130: ubiquitin binding1.39E-02
101GO:0061630: ubiquitin protein ligase activity1.44E-02
102GO:0051087: chaperone binding1.49E-02
103GO:0035251: UDP-glucosyltransferase activity1.59E-02
104GO:0036459: thiol-dependent ubiquitinyl hydrolase activity1.59E-02
105GO:0004298: threonine-type endopeptidase activity1.59E-02
106GO:0008408: 3'-5' exonuclease activity1.59E-02
107GO:0016787: hydrolase activity1.60E-02
108GO:0003756: protein disulfide isomerase activity1.92E-02
109GO:0004842: ubiquitin-protein transferase activity2.06E-02
110GO:0005507: copper ion binding2.18E-02
111GO:0030276: clathrin binding2.26E-02
112GO:0016853: isomerase activity2.38E-02
113GO:0030170: pyridoxal phosphate binding2.40E-02
114GO:0004843: thiol-dependent ubiquitin-specific protease activity2.63E-02
115GO:0016413: O-acetyltransferase activity3.28E-02
116GO:0016597: amino acid binding3.28E-02
117GO:0051213: dioxygenase activity3.42E-02
118GO:0009931: calcium-dependent protein serine/threonine kinase activity3.70E-02
119GO:0042802: identical protein binding3.78E-02
120GO:0016887: ATPase activity3.81E-02
121GO:0004806: triglyceride lipase activity3.84E-02
122GO:0004683: calmodulin-dependent protein kinase activity3.84E-02
123GO:0004222: metalloendopeptidase activity4.43E-02
124GO:0008168: methyltransferase activity4.43E-02
125GO:0030145: manganese ion binding4.58E-02
RankGO TermAdjusted P value
1GO:0005785: signal recognition particle receptor complex0.00E+00
2GO:0005684: U2-type spliceosomal complex0.00E+00
3GO:0045335: phagocytic vesicle0.00E+00
4GO:0005777: peroxisome8.89E-09
5GO:0005829: cytosol1.60E-08
6GO:0005783: endoplasmic reticulum8.12E-06
7GO:0005737: cytoplasm2.24E-05
8GO:0000502: proteasome complex2.64E-05
9GO:0005886: plasma membrane3.56E-05
10GO:0031595: nuclear proteasome complex1.99E-04
11GO:0045334: clathrin-coated endocytic vesicle2.65E-04
12GO:0033185: dolichol-phosphate-mannose synthase complex5.83E-04
13GO:0031314: extrinsic component of mitochondrial inner membrane5.83E-04
14GO:0008541: proteasome regulatory particle, lid subcomplex5.99E-04
15GO:0005782: peroxisomal matrix9.47E-04
16GO:0030139: endocytic vesicle9.47E-04
17GO:0030176: integral component of endoplasmic reticulum membrane9.75E-04
18GO:0031902: late endosome membrane1.16E-03
19GO:0032585: multivesicular body membrane1.35E-03
20GO:0070062: extracellular exosome1.35E-03
21GO:0005968: Rab-protein geranylgeranyltransferase complex1.35E-03
22GO:0031372: UBC13-MMS2 complex1.81E-03
23GO:0072686: mitotic spindle2.31E-03
24GO:0000776: kinetochore2.31E-03
25GO:0031597: cytosolic proteasome complex3.43E-03
26GO:0005778: peroxisomal membrane3.73E-03
27GO:0031305: integral component of mitochondrial inner membrane4.69E-03
28GO:0009514: glyoxysome5.37E-03
29GO:0005786: signal recognition particle, endoplasmic reticulum targeting5.37E-03
30GO:0031901: early endosome membrane6.09E-03
31GO:0005773: vacuole6.55E-03
32GO:0030665: clathrin-coated vesicle membrane6.83E-03
33GO:0008540: proteasome regulatory particle, base subcomplex6.83E-03
34GO:0017119: Golgi transport complex7.61E-03
35GO:0005686: U2 snRNP7.61E-03
36GO:0090404: pollen tube tip8.42E-03
37GO:0005769: early endosome1.29E-02
38GO:0005635: nuclear envelope1.29E-02
39GO:0005774: vacuolar membrane1.57E-02
40GO:0005839: proteasome core complex1.59E-02
41GO:0005741: mitochondrial outer membrane1.59E-02
42GO:0000790: nuclear chromatin2.03E-02
43GO:0005770: late endosome2.26E-02
44GO:0005789: endoplasmic reticulum membrane2.44E-02
45GO:0009504: cell plate2.51E-02
46GO:0005759: mitochondrial matrix2.72E-02
47GO:0000145: exocyst2.76E-02
48GO:0032580: Golgi cisterna membrane3.02E-02
49GO:0005794: Golgi apparatus3.12E-02
50GO:0016020: membrane3.50E-02
51GO:0005788: endoplasmic reticulum lumen3.56E-02
52GO:0000151: ubiquitin ligase complex4.13E-02
53GO:0009507: chloroplast4.56E-02
Gene type



Gene DE type